chromosome, chromosome abnormalities and birth defects Flashcards
dosage compensation: define dosage compensation and explain why sex determination is not solely based on sex chromosome karyotype
1
Q
dosage compensation
A
ensures equivalent gene expression
2
Q
methods of dosage compensation
A
lyonization of X in female; 2 times expression of X in XY male; 0.5X expression in both X genes of hermaphrodites
3
Q
sex determination vs purely karyotype
A
can be chromosomally 1 gender and phenotypically the other if the sex-determining region on Y (SRY) is translocated to the X chromosome
