chromosome abnormalities Flashcards
1
Q
structure of chromosomes
A
2
Q
karyograms
A
represent karyotypes
autosomal homologs are in size order with sex chromosomes at th end
3
Q
karyogram of female wit downs
A
4
Q
what does large scale chromosomal alterations cause
A
miscarriage and individuals born with dev disorders
5
Q
what are the four types of changes in chromosome structure caused by meiosis error
A
Deletion
Duplication
Inversion
Translocation
6
Q
when do rearrangemnts occur
A
during meiosis coz of Mistakes in cross-over and recombination
7
Q
Balanced rearrangements
A
no loss or gain material
swap material between non-homologous chromosomes
Genome is complete therefore no disease
But recombination may affect offspring
8
Q
Unbalanced rearrangements
A
gain or lose material therefore disease effects can be large
9
Q
A
