Chromosomal Translocations Flashcards

1
Q

Burkitt lymphoma

A

t(8;14)

c-myc activation

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2
Q

CML

A

t(9;22) (Philadelphia chromosome)

chromosome 14

BCR-ABL hybrid

“Philadelphia CreaML cheese”

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3
Q

Mantle cell lymphoma

A

t(11;14)

cyclin D1 activation

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4
Q

Follicular lymphoma

A

t(14;18)

BCL-2 activation

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5
Q

APL (M3 type of AML)

A

t(15;17)

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