Chpt 3 Flashcards

1
Q

When a protein is denatured?

A

It’s biological activity is lost.

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2
Q

Which of the following aspects of protein structure is/are most easily disrupted when a protein is heated in neutral solution?

A

Hydrogen bonds.

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3
Q

Which of the following treatments will break disulfide bridges in proteins?

A

Has to be 110 degrees 6M HCL

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4
Q

When protein is heated at 100 degrees in neutral solution, the effects are?

A

Loss of biological function.

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5
Q

Which of the following statements about normal hemoglobin are correct?

A

The iron of hemoglobin remains in the fe2+ state in the course of its normal functioning.

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6
Q

The binding of oxygen to hemoglobin is described as co operative. This means that?

A

The shape of the oxygen dissociation curve of hemoglobin is sigmoid.

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7
Q

Which of the following statements about hemoglobin are correct?

A

Oxygenates hemoglobin is a stronger acid than deoxygenated hemoglobin.

As pH is lowered, the affinity if hemoglobin for oxygen becomes become less.

Each molecule of hemoglobin can combine with four molecules of oxygen.

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8
Q

What does the right shift in hemoglobin oxygen dissociation curve signify?

A

Improved oxygen delivery to tissues.

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9
Q

Hemoglobin A1c is the product of Jon catalyzed reaction of hemoglobin with glucose. Under what circumstances will the proportion of hemoglobin A1c be higher than normal?

A

In a diabetic patient with poor control of blood gluclose.

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10
Q

Amino acids are building blocks of proteins. Which of the following is true?

A

All amino acids have a similar structure

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