Chp 9 Flashcards

1
Q

BC Rxns are what type of sensitivity

A

1,2,3

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2
Q

Type 4 sensitivity is what rxn

A

TC

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3
Q

Type 1 hypersensitivity

A

Immediate
Performed antibodies -person had already encountered antigen
Involve mast and basophils

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4
Q

Mast cells reside where

A

In tissues full of granules
Degran
Effect of granules
-vasodilation

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5
Q

Ex of type 1

A

Hay fever
Hives
Allergies
Anaphylaxis

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6
Q

Type 1 maybe

A

Local or systemic

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7
Q

BC produce what antibody

A

IgE mediated allergic rxn

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8
Q

Effects of granules

A

Vasodilation
Increases capillary permeability
Accumulation of edema

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9
Q

Type 2

A

Cytotoxic

Antibodies directly attach to antigen in target tissue

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10
Q

Type 2 target what

A

Host cell rather than foreign antigen

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11
Q

Two types of type 2

A

Death of target cell

Antibodies block receptor function

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12
Q

Death of target cell means

A

Killed by other components of immune sys

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13
Q

Antibodies blocked mean

A

The receptor function is blocked =myasthenia gravis

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14
Q

Type 3

A
Immune complex
Antigen and antibody combine 
Deposition induced inflammatory
Types
-distant
-local
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15
Q

Type 3 deposition induced where

A

Blood vessels
Kidney
Joins

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16
Q

Distant type 3

A

Ex systemic lupus

Circulate to diff site from formation

17
Q

Local type 3

A

Remain at site

Ex farmers lung

18
Q

Type 4

A

T lymphocyte
Does not depend on antibodies
Response is delayed

19
Q

Type 4 steps

A

Antigen uptake by APC
Memory TC
Release mediators

20
Q

Ex type 4

A

Poison ivy
Metallic injury
Celiac disease

21
Q

Other ex of hypersensitivity

A

Allergies

Autoimmune disease