cholinergic {parasympathetic N.S} Flashcards

1
Q

cholinergic receptors

A

nicotinic

muscarinic

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2
Q

types of muscarinic

A

m1-m5

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3
Q

types of nicotinic and their location

A

Nm-present in skeletal muscle emd plate

Nn-present in ganglia,adrenalmedullary cells,brain ,spinal cord

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4
Q

activator and inhibitor of nm

A

selective activator-phenyltrimethyl ammonium

inhibitor-tubocuranine

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5
Q

activator and inhibitor of nn

A

activator-dimethyl piperazine

inhibitor-hexamethonium

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6
Q

what are parasympathomimetic agents

A

these are compounds that produce similar effect as acetylcholine,they are directly acting(bind to receptor like Ach) or indirectly acting (induce release of ach or inhibit cholinestearase)

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7
Q

direct acting parasympathomimetics

A

cholinesters

cholinomimetic alkaloids

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8
Q

what are cholineesters

A

these are sympathetic derivatives of choline,work at muscarinic receptors

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9
Q

cholineesters

A
  • carbacholchloride
  • methacholine chloride
  • acetylcholinechloride
  • bethanicolchloride
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10
Q

cholinomimetic alkaloids

A

muscarine
pilocarpine
areoline
all are muscarinic

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11
Q

endogenous peptides

A

enkephalin
endorphin
dynorphins

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12
Q

triptans

A

antimigraine meds

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13
Q

opiates receptors

A
mu
kappa
sigma
delta 
epislon
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