cholinergic {parasympathetic N.S} Flashcards
cholinergic receptors
nicotinic
muscarinic
types of muscarinic
m1-m5
types of nicotinic and their location
Nm-present in skeletal muscle emd plate
Nn-present in ganglia,adrenalmedullary cells,brain ,spinal cord
activator and inhibitor of nm
selective activator-phenyltrimethyl ammonium
inhibitor-tubocuranine
activator and inhibitor of nn
activator-dimethyl piperazine
inhibitor-hexamethonium
what are parasympathomimetic agents
these are compounds that produce similar effect as acetylcholine,they are directly acting(bind to receptor like Ach) or indirectly acting (induce release of ach or inhibit cholinestearase)
direct acting parasympathomimetics
cholinesters
cholinomimetic alkaloids
what are cholineesters
these are sympathetic derivatives of choline,work at muscarinic receptors
cholineesters
- carbacholchloride
- methacholine chloride
- acetylcholinechloride
- bethanicolchloride
cholinomimetic alkaloids
muscarine
pilocarpine
areoline
all are muscarinic
endogenous peptides
enkephalin
endorphin
dynorphins
triptans
antimigraine meds
opiates receptors
mu kappa sigma delta epislon