Cholinergic-Blocking Drugs Flashcards
mydriasis
dilation of the pupil of the eye caused by contraction of the dilator muscle of the iris
cholinergic-blocking drugs
drugs that block the action of acetylcholine and substances similar to acetylcholine at receptor sites in the synapse
parasympathetics
drugs that reduce the activity of the parasympathetic nervous system; also called anticholinergics
cholinergic blockers: natural plant alkaloids
atropine [generic], belladonna [Belladonna tincture], hyoscyamine [Levsin], scopolamine [Transderm-Scop]
cholinergic blockers: synthetic and semi-synthetic drugs
benztropine [Cogentin], biperidan [Akineton], darifenacin [Enablex], dicyclomine [Bentyl], fesoterodine [Toviaz], glycopyrrolate [Robinul], homatropine [Isopto Homatropine], ipratropium [Atrovent], mepenzolate [Cantil], methscopolamine [Pamine], oxybutynin [Ditropan], procyclidine [Kemadrin], propantheline [Pro-Banthine], solifenacin [Vesicare], tolterodine [Detrol], trihexyphenidyl [generic], trospium [Sanctura]
cholinergic blockers adverse effects: cardiovascular system
increased heart rate, dysrhythmias (tachycardia, palpitations)
cholinergic blockers adverse effects: central nervous system
excitation, restlessness, irritability, disorientation, hallucinations, delirium, ataxia, drowsiness, sedation, confusion
cholinergic blockers adverse effects: eye
dilated pupils (causing blurred vision), increased intraocular pressure
cholinergic blockers adverse effects: gastrointestinal system
decreased salivation, gastric secretions, and motility (causing constipation)
cholinergic blockers adverse effects: genitourinary system
urinary retention
cholinergic blockers adverse effects: glandular
decreased sweating
cholinergic blockers adverse effects: respiratory system
decreased bronchial secretions
cholinergic blocking drugs
atropine, dicyclomine, glycopyrrolate, oxybutynin, scopolamine, tolterodine