Cholinergic agonist effects (PNS) Flashcards
1
Q
Heart (M2)
A
decrease HR, contractility, conduction=bradycardia
2
Q
Blood pressure (M3)
A
decrease BP
3
Q
Lungs (M3)
A
bronchostriction, increase secretions
4
Q
Temp regulation (M3)
A
increase sweating=heat loss
5
Q
Eye (M3)
A
miosis, increase aqueous humor outflow (glaucoma)
6
Q
GI/GU
A
increase salivation (For xerostomia), increase detrusor contraction (for inc urinary flow), increase motility (paralytic ileus)
7
Q
CNS (M1)
A
memory/cognition/movement (for Alzheimers)
8
Q
NMJ (Nm)
A
muscle contraction (for MG)
9
Q
meds
A
pilocarpine-bethanechol (M)
Neostigmine-physostigmine (indirect)
Edrophonium-Donepezil (indirect)
Organophosphate nerve gases
10
Q
adverse reaction
A
Salivation Lacrimation Urination Defecation GI cramping, motility Eye (miosis)
