Cholinergic/Adrenergic Physiology Flashcards

1
Q

Heart

Cholinergic Agonist

A

M2: Decrease HR

Decrease Contractility

Decrease Conduction through AV node

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2
Q

Blood Vessels

Cholinergic Agonist

A

Vasodilation - Not innervated, drug action only

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3
Q

Blood Pressure

Cholinergic Agonist

A

Decrease BP

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4
Q

Lung

Cholinergic Agonist

A

Bronchoconstriction

Increase secretions

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5
Q

Eye

Cholinergic agonist

A

Miosis

Accommodation (Near vision)

Increase aqueous humor outflow

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6
Q

GI / GU

Cholinergic agonist

A

Increase Salivation

Increase detrusor muscle contraction

Increase motility

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7
Q

Neuromuscular junction

Cholinergic agonist

A

Nm: Muscle contraction

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8
Q

CNS

Cholinergic agonist

A

M: Memory / cognition / movement

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9
Q

Male Genitalia

Cholinergic agonist

A

Stimulates erection

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10
Q

Adrenal Medulla

Cholinergic agonist

A

Nn: Epinephrine and norepinephrine secretion

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11
Q

Lacrimal gland

Cholinergic agonist

A

Stimulates tears

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12
Q

Heart

Cholinergic Antagonist

A

Increase HR

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13
Q

Salivary glands

Cholinergic agonist

A

Copious watery secretion

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14
Q

Blood Vessels

Cholinergic Antagonist

A

Nothing

No cholinergic tone to antagonize

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15
Q

Blood Pressure

Cholinergic antagonist

A

Minimal effects

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16
Q

Lung

Cholinergic antagonist

A

Bronchodilation

Increased drying

17
Q

Eye

Cholinergic antagonist

A

Mydriasis

Blurred vision

Decrease Outflow / Increased Intraocular pressure

18
Q

GI / GU

Cholinergic Antagonist

A

Decreased salivation

Block detrusor muscle

Decrease GI motility

19
Q

NMJ

Cholinergic antagonist

A

Flaccid paralysis

20
Q

CNS

Cholinergic antagonist

A

Sedation / Confusion

21
Q

Heart

Adrenergic agonist

A

B1: Increase HR / contractility

22
Q

Blood Vessels

Adrenergic agonist

A

a1: Vasoconstriction

B2: Vasodilation

23
Q

Blood Pressure

Adrenergic agonist

A

a1: Increase BP

B1: Increase BP

B2: Decrease BP (if unopposed by a1)

24
Q

Lung

Adrenergic agonist

A

B2: Bronchodilation

25
Q

Eye

Adrenergic agonist

A

a1: Mydriasis

B: Increase humor production

26
Q

GI / GU

Adrenergic agonist

A

a2: GI relaxation (Indirect via decreased ACh release)

B2 + B3: Bladder smooth muscle relaxation

a1: Close sphincter

B2: Uterine relaxation

27
Q

NMJ

Adrenergic agonist

A

B2: Muscle tremors

28
Q

CNS

Adrenergic agonist

A

Increased vigilance / focus

29
Q

Male Genitalia

Adrenergic agonist

A

a1: Stimulates ejaculation

30
Q

Salivary glands

Adrenergic agonist

A

a1: Thich viscid secretion

31
Q

Heart

Adrenergic antagonist

A

B1: Decrease HR / contractility

32
Q

Blood Vessels

Adrenergic antagonist

A

a1: Vasodilation

B2: Vasoconstriction

33
Q

Blood pressure

Adrenergic antagonist

A

a1 + B1: Decreased BP

a2 agonist: Decreased BP (Via central effect at vasomotor center)

34
Q

Lung

Adrenergic antagonist

A

B2: Bronchospasm

35
Q

Eye

Adrenergic antagonist

A

B1 + B2: Decrease Aqueous humor production / decrease Intraocular pressure

36
Q

GI / GU

Adrenergic antagonist

A

a1: Open sphincter

37
Q

NMJ

Adrenergic antagonist

A

No effects usually seen

38
Q

CNS

Adrenergic antagonist

A

B: Depressed mood / sleep disturbances