Cholangiocarcinoma Flashcards
1
Q
What was the clinical relevance of the SWOG 0809 trial for extrahepatic biliary cancer?
A
This trial showed adjuvant chemoRT produced favorable results and low toxicity. Randomized trials are warranted.
2
Q
What population was studied in the SWOG 0809 trial for extrahepatic biliary cancer?
A
79 pts with extrahepatic cholangiocarcinoma or gallbladder carcinoma, pT2-T4, or N+, or R1
3
Q
What regimen was studied in the SWOG 0809 trial for extrahepatic biliary cancer?
A
adjuvant capecitabine+gem, then 45 Gy RT LNs and tumor bed plus boost to 54-59 Gy with concurrent capecitabine
4
Q
What were the results of the SWOG 0809 trial for extrahepatic biliary cancer?
A
2-yr OS 65%, median OS 35 mos, LR in 14 pts, DM in 24 pts, combined relapse in 9 pts
