Chlamydia Trachomatis

Question 1

Most common STDs

Answer 1

Chlamydia Trachomatis and Neisseria Gonorrhoea infection

Question 2

Most common bacterial cause of sexually transmitted genital infections

Answer 2

Chlamydia Trachomatis

Question 3

Majority of affected persons are ________ and provide an ongoing reservoir for infection.

Answer 3

Asymptomatic

Question 4

Infants born to mothers through an infected birth canal, _________ and ________ can occur.

Answer 4

Conjunctivitis and pneumonia

Question 5

Incubation period of symptomatic dxs ranges from ____ to _____ days following infection.

Answer 5

5 to 14 days

Question 6

It’s _______ how long those with ______ dxs may carry the infection.

Answer 6

Unclear, asymptomatic

Question 7

6 Clinical Syndromes in Females

Answer 7

1) Genitourinary tract infection
2) Cervicitis
3) Dysuria-pyuria syndrome
4) Pelvic Inflammatory Dxs
5) Perihepatitis (Fitz-Hugh-Curtis Syndrome)
6) Complications of pregnancy

Question 8

Genitourinary tract infection usually occurs at the ______ and _______.

Answer 8

Cervix (ascending infection) and urethra

Question 9

Majority of females (85%) of females are ______ in Cervicitis.

Answer 9

Asymptomatic

Question 10

Symptoms in Cervicitis

Answer 10

Change in vaginal discharge
Intermenstrual vaginal bleeding - in bwtn periods
Post-coital bleeding - occurring after sex

Question 11

Dysuria-pyuria syndrome is due to ____.

Answer 11

Urethritis

Question 12

Dysuria-pyuria

Answer 12

Dysuria is burning, tingling, or stinging of the urethra and meatus associated with voiding.

Question 13

C.trachomatis can ascend to the upper reproductive tract (uterus, fallopian tubes, and ovaries) where ______ can occur.

Answer 13

Pelvic Inflammatory Dxs

Question 14

Symptoms of Pelvic Inflammatory Dxs (PID)

Answer 14

Abdominal and pelvic pain (especially in setting of Cervicitis or in Chlamydia infection)

Question 15

Signs of Pelvic Inflammatory Dxs (PID)

Answer 15

Cervical motion
Uterine or adnexal tenderness

Question 16

PID due to C.trachomatis is associated with higher rates of….

Answer 16

Subsequent tubal infertility, ectopic pregnancy, and chronic pelvic pain.

Question 17

Perihepatitis (Fitz-Hugh-Curtis Syndrome)

Answer 17

Inflammation of the liver capsule and adjacent peritoneal surfaces.

Question 18

Perihepatitis (Fitz-Hugh-Curtis Syndrome) is associated with ______ Or _____ but no….

Answer 18

Right upper quadrant pain or pleuritic pain but no liver enzyme abnormalities

Question 19

Chlamydia genital infection during pregnancy can increase…

Answer 19

The risk for premature rupture of the membranes, preterm delivery, and low-birthweight infants.

Question 20

3 Clinical Syndromes in Males

Answer 20

1) Urethritis
2) Epididymitis
3) Prostatitis

Question 21

Epididymitis

Answer 21

Unilateral testicular pain and tenderness, hydrocele, and palpable swelling of the epididymis.

Question 22

Prostatitis

Answer 22

Dysuria, urinary dysfunction, pain with ejaculation, and pelvic pain.

Question 23

5 Clinical Syndromes Common to both Females and Males

Answer 23

1) Conjunctivitis
2) Pharyngitis
3) Proctitis and Rectal infection
4) Genital lymphogranuloma venereum (LGV)
5) Reactive arthritis / reactive arthritis triad (RAT)

Question 24

Complete reactive arthritis triad

Answer 24

Arthritis, conjunctivitis or uveitis, and urethritis or Cervicitis

Question 25

Most common inciting pathogen for sexually acquired reactive arthritis

Answer 25

Chlamydia Trachomatis

Question 26

Diagnostic techniques include…

Answer 26

Nucleic acid amplification testing (NAAT)
Culture
Antigen detection
Genetic probs

Question 27

Diagnostic technique of choice

Answer 27

Nucleic acid amplification testing (NAAT)

Question 28

Not useful for the diagnosis of Chlamydia Infections

Answer 28

Microscopy

Question 29

Preferred specimen for females

Answer 29

Vaginal swab and First-catch urine specimen

Question 30

Preferred specimen for testing in Males

Answer 30

First-catch urine

Question 31

Treatment depends on

Answer 31

Actual symptoms and specific infections (urethritis, Cervicitis, proctitis)

Question 32

Treatment of Chlamydia trachomatis with Gonorrhoea

Answer 32

Ceftriaxone 500mg IV or IM with Ligno (for numbness)

Question 33

Treatment for non-pregnant women

Answer 33

Doxycycline 100mg bd (twice daily) x 7 days (up to 3 wks in proctits)

Question 34

Drug Alternatives for Treatment

Answer 34

Azithomycin 1g stat (immediate)
Fluoroquinolones
Levofloxacin
Ofloxacin

Question 35

Treatment for Pregnant women

Answer 35

Either Azithromycin 1g stat (immediate) or Oral Amoxicillin 500mg Q8H (every 8 hrs) x 7 hrs