Chlamydia Trachomatis Flashcards

1
Q

Most common STDs

A

Chlamydia Trachomatis and Neisseria Gonorrhoea infection

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2
Q

Most common bacterial cause of sexually transmitted genital infections

A

Chlamydia Trachomatis

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3
Q

Majority of affected persons are ________ and provide an ongoing reservoir for infection.

A

Asymptomatic

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4
Q

Infants born to mothers through an infected birth canal, _________ and ________ can occur.

A

Conjunctivitis and pneumonia

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5
Q

Incubation period of symptomatic dxs ranges from ____ to _____ days following infection.

A

5 to 14 days

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6
Q

It’s _______ how long those with ______ dxs may carry the infection.

A

Unclear, asymptomatic

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7
Q

6 Clinical Syndromes in Females

A

1) Genitourinary tract infection
2) Cervicitis
3) Dysuria-pyuria syndrome
4) Pelvic Inflammatory Dxs
5) Perihepatitis (Fitz-Hugh-Curtis Syndrome)
6) Complications of pregnancy

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8
Q

Genitourinary tract infection usually occurs at the ______ and _______.

A

Cervix (ascending infection) and urethra

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9
Q

Majority of females (85%) of females are ______ in Cervicitis.

A

Asymptomatic

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10
Q

Symptoms in Cervicitis

A

Change in vaginal discharge
Intermenstrual vaginal bleeding - in bwtn periods
Post-coital bleeding - occurring after sex

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11
Q

Dysuria-pyuria syndrome is due to ____.

A

Urethritis

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12
Q

Dysuria-pyuria

A

Dysuria is burning, tingling, or stinging of the urethra and meatus associated with voiding.

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13
Q

C.trachomatis can ascend to the upper reproductive tract (uterus, fallopian tubes, and ovaries) where ______ can occur.

A

Pelvic Inflammatory Dxs

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14
Q

Symptoms of Pelvic Inflammatory Dxs (PID)

A

Abdominal and pelvic pain (especially in setting of Cervicitis or in Chlamydia infection)

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15
Q

Signs of Pelvic Inflammatory Dxs (PID)

A

Cervical motion
Uterine or adnexal tenderness

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16
Q

PID due to C.trachomatis is associated with higher rates of….

A

Subsequent tubal infertility, ectopic pregnancy, and chronic pelvic pain.

17
Q

Perihepatitis (Fitz-Hugh-Curtis Syndrome)

A

Inflammation of the liver capsule and adjacent peritoneal surfaces.

18
Q

Perihepatitis (Fitz-Hugh-Curtis Syndrome) is associated with ______ Or _____ but no….

A

Right upper quadrant pain or pleuritic pain but no liver enzyme abnormalities

19
Q

Chlamydia genital infection during pregnancy can increase…

A

The risk for premature rupture of the membranes, preterm delivery, and low-birthweight infants.

20
Q

3 Clinical Syndromes in Males

A

1) Urethritis
2) Epididymitis
3) Prostatitis

21
Q

Epididymitis

A

Unilateral testicular pain and tenderness, hydrocele, and palpable swelling of the epididymis.

22
Q

Prostatitis

A

Dysuria, urinary dysfunction, pain with ejaculation, and pelvic pain.

23
Q

5 Clinical Syndromes Common to both Females and Males

A

1) Conjunctivitis
2) Pharyngitis
3) Proctitis and Rectal infection
4) Genital lymphogranuloma venereum (LGV)
5) Reactive arthritis / reactive arthritis triad (RAT)

24
Q

Complete reactive arthritis triad

A

Arthritis, conjunctivitis or uveitis, and urethritis or Cervicitis

25
Most common inciting pathogen for sexually acquired reactive arthritis
Chlamydia Trachomatis
26
Diagnostic techniques include…
Nucleic acid amplification testing (NAAT) Culture Antigen detection Genetic probs
27
Diagnostic technique of choice
Nucleic acid amplification testing (NAAT)
28
Not useful for the diagnosis of Chlamydia Infections
Microscopy
29
Preferred specimen for females
Vaginal swab and First-catch urine specimen
30
Preferred specimen for testing in Males
First-catch urine
31
Treatment depends on
Actual symptoms and specific infections (urethritis, Cervicitis, proctitis)
32
Treatment of Chlamydia trachomatis with Gonorrhoea
Ceftriaxone 500mg IV or IM with Ligno (for numbness)
33
Treatment for non-pregnant women
Doxycycline 100mg bd (twice daily) x 7 days (up to 3 wks in proctits)
34
Drug Alternatives for Treatment
Azithomycin 1g stat (immediate) Fluoroquinolones Levofloxacin Ofloxacin
35
Treatment for Pregnant women
Either Azithromycin 1g stat (immediate) or Oral Amoxicillin 500mg Q8H (every 8 hrs) x 7 hrs