Chiro Essentials Part 1 Flashcards
Abdominal pain blue gum line and constipation indicates?
Lead poisoning
Abdominal pain and tenderness in the right iliac fossa indicates?
Appendicitis
Abdominal pain following an alcoholic binge indicates?
Pancreatitis
Abdominal pain in the right iliac fossa and diarrhea indicates?
Crohn’s disease
Abdominal pain in the left iliac fossa blood in stool in a young female indicates?
Ulcerative colitis
Abdominal pain in the left iliac fossa blood in stool in an older male indicates?
Diverticulitis
Abdominal pain splenomegaly in a black child indicates?
Sickle Cell
Adrenal hemmorrhage and shock indicates?
Waterhouse-Friderichsen syndrome
Amenorrhea no lactation after postpartum hemorrhage indicates?
Sheehan’s syndrome
Arachnodactyly lens dislocation hyper-mobile joints indicates?
Marfan’s disease
Argyll-Robertson pupil aortic aneurysm and angina pectoris indicates?
Tertiary syphilis
Ataxia heart problems and scoliosis indicates?
Friedreich’s disease
Beefy red tongue and fatigue indicates?
Vitamin B12 deficiency
Bilateral hilar lymphadenopathy and erythema nodosum indicates?
Sarcoidosis
Bilateral ptosis diploplia and difficulty chewing found in females indicates?
Myasthenia Gravis
Bitot’s spots in the eye indicates?
Vitamin A deficiency
Bladder or bowel control problem indicates?
cauda equina syndrome
Bleeding swollen gums indicates?
Scurvy
Blue lips swollen ankles and dyspnea indicates?
Chronic bronchitis
Blue sclera and frequent fractures as an infant indicates?
osteogenesis imperfecta
Bone pain head enlargement and deafness indicates?
Paget’s Disease of bone
Bronze skin cirrhosis and diabetes mellitus indicates?
Hemochromatosis
Buffalo hump obesity and purplish abdominal striae indicates?
Cushing’s syndrome
Buboes in the groin sign of the groove indicates?
Lymphogranuloma venereum
Bull’s eye rash indicates?
Lyme disease
Butterfly rash and multiple painful joints in a young female indicates?
Systemic Lupus Erythematosus
Cafe-au-lait spots and skin nodules indicates?
Neurofibromatosis
Calf pseudohypertrophy and a positive Gower’s sign indicates?
Duchenne’s muscular dystrophy
Cape-like distribution of loss of pain indicates?
Syringomyelia
Caput Medusa indicates?
Cirrhosis with portal hypertension
Carditis chorea polyarthritis and subcutaneous nodules indicates?
Rheumatic fever
Casal’s necklace indicates?
Pellagra
Cat scratch fever and local lymphadenitis indicates?
Cat Scratch Disease
Cauliflower like lesions on the hands or genitals indicates?
Human Papilloma Viral Infection
Cherry red spots on the macula indicates?
Tay-Sachs disease
Cherry red skin and headaches indicates?
Carbon Monoxide poisoning
Chest pain worse on lying down and better while sitting forward indicates?
Pericarditis
Chest pain worse with exertion and better with rest indicates?
Angina pectoris
Chest pain with sweating and feeling of apprehension indicates?
Myocardial Infarction
Chills fever vomiting and costovertebral angle tenderness indicates?
Pyelonephritis
Chorea and dementia indicates?
Huntington’s disease
Chronic non healing ulcer on ear or nose indicates?
Basal cell carcinoma
Cirrhosis and Kayser-Fleisher rings indicates?
Wilson’s disease
Clubbing and cyanosis in an infant with heart murmur indicates?
Fallot’s tetralogy
Condylomata accuminata indicates?
Human Papilloma virus infection
Condylomata lata indicates?
Secondary syphilis
Coryza conjunctivitis and “C” oplick spots indicates?
Measles
Deep labored breathing with acetone smell on breath indicates?
Diabetic ketoacidosis
Dermatitis diarrhea and dementia indicates?
Pellagra
Dry eyes mouth and arthritis indicates?
Sjogren’s syndrome
Dysphagia glossitis and iron deficiency anemia indicates?
Plummer-Vinson syndrome
Dyspepsia worse with eating food indicates?
Gastric type of peptic ulcer disease
Elastic skin with hypermobile joints indicates?
Ehlers-Danlos syndrome
Enlarged nerves and anesthetic hypopigmented rashes indicates?
Leprosy
Fair fat female over 40 with abdominal pain indicates?
Cholecystitis
Fever cough chest pain in a parrot breeder indicates?
Bird fancier’s disease
Fever headache and skin rash on wrist and feet indicates?
Rocky Mountain Spotted Fever
Fever conjuctivitis coryza and fine rash on trunk indicates?
Measles
Fever neck stiffness and headaches indicates?
Meningitis
Fever night sweats weight loss cough or hemoptysis indicates?
Tuberculosis
Fever maculopapulovesicular rash on trunk indicates?
Chickenpox
Frequent urination with burning on micturition
Urinary Tract Infection
Frothy urine recurrent infections with normal blood pressure indicates?
Nephrotic syndrome
Frothy malodorus vaginal discharge indicates?
Trichomonas vaginitis
Galactorrhea and amenorrhea indicates?
Prolactinoma
Gumma indicates?
Tertiary syphilis
Gottron’s papules and heliotrope eyelids indicates?
Dermatomyositis
Gout and self mutilation in a child due to pain insensitivity indicates?
Lesch-Nyhan syndrome
Haygrath’s nodes indicates?
Rheumatoid Arthritis
Heartburn that is worse on lying down after meals indicates?
Gastro-Esophageal Reflux Disease (GERD)
Heat intolerance fine tremors weight loss or exopthalmos indicates?
Hyperthyroidism
Heberden’s and Bouchard’s nodes indicates?
Osteoarthritis
Hematemesis following protracted vomiting or wretching indicates?
Mallory Weiss syndrome
Hemoptysis and in a chronic cigarette smoker indicates?
Lung cancer
Hemoptysis and hematuria indicates?
Goodpasture syndrome
Honey colored crusts on the face near the mouth and nose indicates?
Impetigo
Hyperpigmented oral cavity and intestinal polyps indicates?
Peutz-Jegher syndrome
Hyperpigmented skin creases bronze skin and fatigue indicates?
Addison’s disease
Hypertension hyperkalemia and metabolic acidosis indicates?
Conn’s disease
Hypertension exopthalmos and goiter indicates?
Graves disease
Indurated painless and penile lesion indicates?
Primary syphilis
Infant with red hair and swollen abdomen indicates?
Kwashiorkor
Infant with microcephaly and rocker-bottom feet indicates?
Trisomy 18 (Edwards Syndrome)
Infant with microcephaly and indistinct philtrum indicates?
Fetal Alcohol Syndrome
Infant with mongoloid eyes and mental retardation indicates?
Trisomy 21 (Down Syndrome)
Irregularly irregular breathing indicates?
Biot’s respiration
Jaundice chills and fever indicates?
Ascending cholangitis
Jaundice ascites and firm non tender hepatomegaly indicates?
Cirrhosis
Jaundicee with tender hepatomegaly indicates?
Hepatitis
Large spatulate hands protruding jaw indicates?
Acromegaly
Loss of outer third of eyebrows and slow reflexes indicates?
Hypothroidism
Low back pain bamboo spine in young male adult indicates?
Ankylosing Spondylitis
Lower abdominal pain and 6-8 weeks of amenorrhea indicates?
Ectopic pregnancy
Koilonychia and pale mucous membranes indicates?
Iron deficiency anemia
Koplick spots and fever followed by fine maculopaular rash indicates?
Measles
Magenta colored tongue indicates?
Vitamin B2 deficiency
Male child with recurrent infection and no B cells indicates?
Bruton’s disease
Mental retardation large scrotal tongue and umbilical hernia indicates?
Down syndrome
Middle aged male smoker with intermittent claudication indicates?
Buerger’s disease
Midsystolic click and atypical chest pain indicates?
Mitral Valve Prolapse
Mole with irregular margins change in color size indicates?
Malignant melanoma
Mucoid urethral discharge in a sexually active male indicates?
Chlamydia urethritis
Muscle cramps with a positive Chvostek test indicates?
Hypoparathyroidism
Newborn with paralyzed arm after difficult vertex delivery indicates?
Erb-Duchenne palsy
Newborn with claw hand after difficult breech delivery indicates?
Klumpke’s palsy
Night blindness dry eyes/skin indicates?
Vitamin A deficiency
Nocturnal back pain recurrent infections and fatigue indicates?
Multiple Myeloma
Obesity hirsuitism and irregular periods indicates?
Polycystic Ovarian syndrome
Osler nodes Janeway nodules or Roth spots indicates?
Subacute Bacterial Endocarditis
Painful pale cold fingers and toes indicates?
Raynaud’s syndrome
Painful fingers and wrists bilaterally with morning stiffness (>1 hr) indicates?
Rheumatoid Arthritis
Painful hip with a limp in a young child indicates?
Legg-Calve-Perthes disease
Painful hip with a limp in an overweight teenager indicates?
Slipped Capital Femoral Epiphysis
Painful pulseless pale perishingly cold limb indicates?
Arterial embolism
Ohio Valley fever
Histoplasma capsulatum
San Joaquin Valley Fever
Coccidioides immitis
Spokes of wheel appearance
Paracoccidioides brasiliensis
Decaying vegetation
aspergillus fumigatus
Wright Giemsa stain
Parasites and syphilis
Spread by bat droppings
Histoplasma capsulatum
Causes meningitis spread by pigeon poop
cryptococcus neoformans
Causes pneumonia in an immune compromised patient
Pneumocystis jiroveci (carinii)
Ziehl-Neelsen stain
Mycobacterium tuberculosis
Percentage of true positive
Sensitivity
Percentage of true negative
Specificity
Used to exclude a disease if test is negative ( SnOUT)
Sensitivity
Used to include a diagnosis if test is positive ( SpIN)
Specificity
Sudden increase in the number with a disease locally
Epidemic
Normal occurrence of disease in a particular locally
Endemic
Sudden increase in the number with a disease worldwide
Pandemic
Number of people with the disease at a given time
Incidence
Number of people who have a particular disease
Morbidity rate
Number of people who die from a particular disease
Mortality rate
Epidemiology or Disease Triangle
Host agent (microbe) and environment
Antigenic shift (virus) spores (bacteria/fungus) cysts ( protozoa)
Microbial adaptations
Disease that has newly appeared
Emerging Disease
Previously known disease that has increased or spread
re-emerging disease
Bacteria and fungi form spores and protozoa form cysts
Pathogen adaptations to environment
Viral adaptation to the environment and host
Antigenic shift
Exposure of milk to progressively higher temperatures
Pasteurization
Use of chemicals to destroy most pathogens
disinfection
Allows water to pass through pores of different sizes
Filtration
Use of aluminum to precipitate material from water
Flocculation
Allows the precipitate to settle out
Sedimentation
Adds anaerobic bacteria to break down organic matter
sludge digestion
Allows water to pass through sand
sand filtration
Passes oxygen through to kill anaerobic bacteria
aeroation
Addition of chlorine to kill all remaining micro-organisms
Chlorination
Anecdotes case study case control cohort study or RCT
Hierarchy of evidence
Describes and interprets an individual case
Case study
Comparing outcomes of those with and without disease
Case Control Study
Follows samples prospectively with respect to disease
Cohort study
Random allocation to experimental or control group
Randomized Clinical Trial
Combines all outcomes and summarizes the findings
Systematic review
Subset of systematic review focused on one conclusion
Meta Anaylsis
Inspect meat and milk
Department of Agriculture
Drug and cosmetic quality and health product advertisement
Food and Drug Administration
Disease surveillance and restaurant inspection
Department of Public Health
Monitors Air and Water quality
Environmental Protection Agency
Monitors quality of diary products
US diary associated
Monitors workplace safety and hazardous material disposal
Occupational Safety Health Admin.
Epidemiological research and health stats
Centers of Disease Control
Oversees health care to the underserved
Health services Administration
Oversees funding for disease research
National Institutes of Health
Recent emerging disease spread by infected body fluids
Ebola
Spread by the vector lxodes scapularis
Lyme disease
Emerging disease spread by body fluids from infected rats
Hantavirus infection
Spread by working with infected birds
Severe Acute Respiratory Syndrome
Spread by working with infected pigs
H1N1 influenza
Emerging disease spread by contact with infected camels
Middle East Respiratory Syndrome
Kills more people in the USA than AIDs
Methicillin Resistant Staph. Aureus
Process in which there is loss of hydrogen electrons
Oxidation
Process in which there is a gain of hydrogen electrons
Reduction
Replacement of hydrogen by carboxyl group (-COOH)
Carboxylation
Substance which speeds up the rate of chemical reactions
Enzyme
Inactive precursor protein with an additional peptide attached
Pro-enzyme
Enzyme that catalyzes the addition of carboxyl broup
Carboxylase
Removal of the carboxyl group (-COOH)
Decarboxylation
Reaction that combines H20 with a salt to produce acid and base
Hydrolysis
Enzyme that causes hydrolysis
Hydrolase
Movement of a phosphate (PO4) from one molecule to another
Phosphorylation
Enzyme which adds a phosphate from an organic compound
Phosphorylase
Enzyme that removes a phosphate from an organic compound
Kinase
Enzyme that catalyzes the transfer of one group to another
Transferase
Enzyme that makes an isomer ( same chemical composition)
Isomerase
Molecule with the same composition but different chemical structure
Isomer
Isomerase enzyme which changes the configuration of a molecule
Mutase
Number of Factors that affect enzyme activity
Three
Temperature pH and concentration of the substrate
Affects enzyme activity
Maximum velocity of a reaction
Vmax
Michaelis-Menten constant
Kmax
The amount of substrate required to reach 1/2 of the Vmax
Kmax
A substance which slows down the rate of an enzyme reaction
Inhibitor
Competition and allosterism
Enzymatic regulation
Actively competes with substrate for the active site
Competition
Changes in activity by acting on a site other than the active site
Allosterism
Chemical bond between two amino acids
Peptide bond
Chemical bond between the base bases found in DNA
Hydrogen bond
Chemical bond between glycerol and fatty acids
Ester bonds
Chemical bond between two sugars
Glycosidic bond