CHIP and ATAC-Seq

Question 1

Where does CHIP-seq stand for?

Answer 1

Chromatin Immunoprecipitation Sequencing; you basically can determine the binding spot of a protein (TF) on the Chromatin (open regions); It identifies the binding sites of DNA-associated proteins (motifs) and can be used to map global binding sites for a given protein

Question 2

Where does ATAC-seq stand for?

Answer 2

Assay for Transposase-Accessible Chromatin. DNA can be transcribed when the chromatin is loosened; allowing transposases to bind and help us answer which part of the chromatin the GOi is transcribed