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Anti-Infectieux 1 > Chimie des Antibactériens > Flashcards

Chimie des Antibactériens Flashcards

1
Q

Quelle enzyme est inhibée par les sulfonamides?

A

dihydroptéroate synthase (sulfo miment PABA –> substrat)

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2
Q

Quelle enzyme est inhibée par les analogues du folates (trimethoprim)?

A

dihydrofolate réductase

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3
Q

Qu’est-ce que les quinolones inhibent?

A

ADN gyrase

topoisomérase IV

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4
Q

Pourquoi est-il important d’avoir un systeme bicylique chez les Beta-Lactams?

A

Profère une tension particulière au cycle beta-lactam

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Anti-Infectieux 1 (3 decks)

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