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Medicaments Anti-infectieux 1 > Chimie AB > Flashcards

Chimie AB Flashcards

1
Q

Fluoroquinolones

A

2 gen:
Norfloxacin
Ciproflixacin

3e gen:
Ofloxacine
Levoflixacine

4e gen
Moxifloxacine

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2
Q

Norfloxacin

A

Noroxin
Norflox

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3
Q

Ciprofloxacine

A

Cipro
Ciloxan

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4
Q

Oflixacine

A

Floxin
Ocuflox

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5
Q

Levofloxacine

A

Levaquin

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6
Q

Moxifloxacine

A

Avelox
Vigamox

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7
Q

Inh synthèse et fct ADN

A

Sulfonamide
Trimethoprime
Quinolones, fluoroquinolones

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8
Q

Inh paroi cell

A

B lactamine
Autres

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9
Q

B lactamine

A

Pénicilline
Cephalosporine
Monobactam
Carbapenem

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10
Q

Autres inh paroi cell

A

Bacitracine
Vancomycine
Daptomycine

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11
Q

Pen fermentation

A

Pénicilline G
pénicilline V

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12
Q

Pen semi-synt résistante B lactamamase Po

A

Cloxacilline

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13
Q

Pen semi-synt large spectre Po

A

Ampicilline
Amoxicilline
Pivampicilline

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14
Q

Pen IV

A

Carbenicilline
Carfecilline

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15
Q

Étude structure activité cephalosporine

A

-act plus faible que pen
-Spectre plus intéressant que Pen
-Biod PO depend: NH2 en 7 , gr non chargé en 3
-bouclier stérique: diminue act
- apparition rapide résistance surtout pr gram-

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16
Q

Céphalosporine 1 gen

A

Cephalexine
Cefadroxil

17
Q

Cephalosporine 2 gen PO

A

Cefaclor
Cefprozil
Cefuroxime axetil

18
Q

Cephalosporine 3e gen

A

Cefixime

19
Q

Études relation structure activité pen

A

-présence gr hydrophobe chaîne lat: augmente act gram +
- augmente caractère hydrophobe: pas de changement gram+ , diminue act gram-
- gr hydrophile: augmente act gram-

20
Q

Acide clavulanique

A

Peu act antibact
Puissant inh b lactamases
Avec Pen pr:
diminuer dose Pen
Aug spectre act

21
Q

Tetracyclines

A

Tetracycline
Doxycycline
Monocycline

22
Q

Macrolides

A

Erythromycine
Clarythromycine
Azithromycine

Medicaments Anti-infectieux 1 (2 decks)

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