Child with Cancer Flashcards
Most common childhood cancer
Leukemia
What Causes Cancer
Carcinogens
Immune Disorders
Chromosome abnormality
History Assessment
Presenting illness Previous illnesses Family history or cancer Present state of health of immediate family Developmental milestones Psychosocial or family concerns ASK ABOUT ANY DEATH UNDER 50
Cardinal Symptoms of Cancer
Unusual mass or swelling Unexplained paleness or loss of energy Sudden tendency to bruise Persistent, localized pain or limping Prolonged unexplained fever or illness Frequent headaches and vomiting Eye or vision changes Excessive and rapid weight loss
Staging
Diagnoses of cancer
Type, severity and spread of cancer cells at the time of diagnosis
All tests are painful – use sedation
Diagnosed at a later stage – poor prognosis
CBC with ANC
CBC with Absolute Neutrophil count
Degree of anemia and infection
<500 IS CRITICAL
**Leukemia
Electrolyte Panel
Type of diagnostic test
Look at renal and liver function
Disruption of healthy cells
Elevated uric acid in leukemia
Tumor Markers
Type of diagnostic test
Metabolities or part of the cancer cells detected in serum or urine
**Neuroblastoma
Lumbar Puncture
Type of diagnostic test
Conscious sedation
Lie still and flat after – to decrease spinal headahce
Monitor site for bleeding and infection!
Routinely used for metastasis in the brain for leukemia
Bone Marrow Aspirate
Type of diagnostic test
Conscious sedation
Prep children! They will not feel it but could be awake
Large band aide on their hip
Monitor for bleeding
Detective test for leukemia and solid tumors
Aspirate the bone marrow – fatty not red
CT and MRI
Type of diagnostic test
CT, MRI and PET
Being used to visualize tumors and begin the diagnostic
Do not hurt but you have to stay still
Treatment: Surgery
Used to remove all the tumor or debulk it
Most successful when the tumor is encapsulated and has not spread
Treatment: Radiation Therapy
Curative or relief of symptoms by shrinking the tumor
Radiation sickness is the anorexia and NV that occurs most with GI irradiation
Antiemetic prior to procedure may help
Skin is tender!
Treatment: Chemotherapy
Primary form of treatment
Need a central line – lessons the chance of skin or tissue damage and irritation
Anticipate pt symptoms!!
Look at ANC counts
Treatment: Biotherapy
Use remodeled antibiodies to target cancer cells only
Limits side effects of the therapy
Treatment: Bone Marrow & Stem Cell Transplant
Treatment choice for some cancers (Leukemia)
Total body irradiation and intensive chemo to kill all cancer cells and all bone marrow cells
Need a good match!!
At risk for Graft VS. Host
Use cord blood for hematopoietic stem cell is on the rise
Leukemia
Most common childhood cancer
Disease of the bone marrow and lymphatic system
Unrestricted proliferation of immature WBC’s in the blood
AML and ALL are the most common
ALL has a better prognosis
Can infiltrate CNS via blood or lymph system – neuro signs and symptoms
Frequent LPs to monitor for cells in the CSF
Leukemia Goals
Remission
Considered “cured” if no cancer cells after 5 years
Harder to achieve remission if cancer cells reappear within 5 years
Leukemia Treatment
Primary chemo, some radiation
Bone marrow and stem cell transplant to consider