Child Development 02.03.2020 Flashcards

1
Q

Barker hypothesis

A

adverse nutrition in early life, including prenatally as measured by birth weight, increased susceptibility to the metabolic syndrome

  • risk of deaths higher both when obese and underweight as a child.
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2
Q

What are the 4 domains of child development?

A
  • gross motor skills and posture
  • fine motor skills and vision
  • language and speech skills (incl. hearing)
  • social skills, emotional and behaviour
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3
Q

History taking re child development problems

A
  • Antenatal – illnesses/infections; medications; drugs; environmental exposures
  • Birth –Prematurity, Prolonged/complicated labour
  • Postnatal – illnesses/infections; Trauma
  • Consanguinity – increases chances of chromosomal or autosomal recessive conditions
  • Developmental milestones from parent
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4
Q

Examinations re child development problems

A
  • Growth parameters – height, weight and head circumference
  • Dysmorphic features
  • Neurological examination and skin
  • Systems examination to identify associations, syndromes
  • Standardised developmental assessment – SOGSII, Griffiths
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5
Q

management of child development issues

A

(Investigations – depends on suspected cause but may include cytogenetic studies; metabolic screen (thyroid, renal, liver and bone profiles); blood ammonia and lactate; urine and blood organic and amino acids; creatine kinase; imaging – CT, MRI; EEG; nerve and muscle biopsy.

Other professionals – referral to members of the multidisciplinary team (MDT) would help identify problems and target input.

The multidisciplinary team – the many professionals who may be involved in the care of children with developmental problems.

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6
Q

What are some common/typical developmental problems?

A
  • Cerebral palsy
  • autism spectrum disorder (ASD)
  • attention deficit hyperactivity disorder (ADHD)
  • learning disability
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7
Q

Cerebral palsy

A
  • A disorder of movement and posture arising from a non-progressive lesion of the brain acquired before the age of 2 years.
  • Incidence 1-2 per 1000 live births
  • Most causes (~80%) are antenatal
  • Presentation may evolve and vary with age
  • Associated problems exist – learning difficulties, epilepsy, visual impairment, hearing loss, feeding difficulties, poor growth, and respiratory problems.

Management
- Aim is to minimise spasticity and manage associated problems

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8
Q

ASD

A
  • Autism spectrum disorder
  • Prevalence is 3-6 per 1000 live births
  • Boys>girls
  • Usually presents between 2 – 4 years of age
  • Features include
    (1) impaired social interaction;
    (2) speech and language disorder; and
    (3) imposition of routines with ritualistic and repetitive behaviour.
  • Comorbidities include learning and attention difficulties, and epilepsy

Management: Intensive support for child and family

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9
Q

ADHD diagnostic criteria

A

(1 )Inattention;

(2) Hyperactivity;
(3) Impulsivity;
(4) Lasting > 6 months;
(5) commencing < 7 years and inconsistent with the child’s developmental level

These features should be present in more than one setting, and cause significant social or school impairment.

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10
Q

ADHD

A

= attention deficit hyperactivity disorder

  • These children also have an increased risk of: conduct disorder, anxiety disorder & aggression
  • Risk factors – Boys > girls, ratio 4:1; Learning difficulties and developmental delay
  • Neurological disorder, e.g. epilepsy, cerebral palsy; first-degree relative with ADHD; family member with depression, learning disability, antisocial personality or substance abuse
  • A significant proportion of children with ADHD will become adults with antisocial personality and there is an increased incidence of criminal behaviour and substance abuse.
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11
Q

Management of ADHD

A
  • Psychotherapy – Behavioural therapies
  • Family therapy
  • Drugs – If behavioural therapy alone insufficient; stimulants, e.g. methylphenidate (Ritalin), amphetamines (dexamphetamine)
  • Diet – Some children benefit noticeably from exclusion of certain foods from their diet, e.g. red food colouring
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12
Q

Learning disability

A
  • Prevalence of moderate learning difficulty is 30 per 1000 children
  • Prevalence of severe learning difficulty is 4 per 1000 children
  • 25% of children with severe learning disability have no identifiable cause
  • Causes include – (i) chromosome disorders (30%); (ii) other identifiable syndromes (20%); (iii) postnatal cerebral insults (20%); (iv) metabolic or degenerative diseases (1%)
  • Classified as mild, moderate, severe or profound
  • May present with reduced intellectual functioning, delay in early milestones, dysmorphic features, ± associated problems (epilepsy, sensory impairment, ADHD)
  • Management : Involves establishing a diagnosis and input from the multidisciplinary team with long term follow up.
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13
Q

What does developmental progress depend on?

A

depends on the interplay between biological and environmental influences. It follows a constant pattern, although at variable rates, among children.

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14
Q

Normal child development

A
  • Development is the global impression of a child which encompasses growth, increase in understanding, acquisition of new skills and more sophisticated responses and behaviour. It serves to endow the child with increasingly complex skills in order to function in society.
  • Limit ages are the age by which they should have been achieved = 2 standard deviations from the mean. They indicate cause of major concern.
  • Developmental progress can be monitored or identified either through developmental screening or by the use of standardised developmental tools.
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15
Q

What are the three main patterns of abnormal development?

A

Refers to the slow acquisition of skills and follows three main patterns:

(1) slow but steady;
(2) plateau; and
(3) regression.

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16
Q

Abnormal development

A
  • refers to the slow acquisition of skills
  • delay may occur in one or more domains
  • Biological factors may impact on development – e.g. folate deficiency increases the risk of neural tube defects which, in its most severe form, can result in limb paralysis, neurogenic bladder and bowel; and intellectual impairment.
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17
Q

When is a child able to sit?

A

around 6 months

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18
Q

When does a child acquire finer motor skills?

A

around 8 months

19
Q

measurement results in achondroplasia

A

Achondroplasia has normal sitting height but short legs.

Skeletal dysplasia, something gone wrong with the genes that determine bone growth etc.

20
Q

How may children present with developmental concerns

A

Children may present with developmental concerns either through

(i) identification of antenatal or postnatal risk factors;
(ii) developmental screening; or
(iii) concerns raised by parents or other healthcare professionals.
- > Thus, these children may present at any age.

21
Q

When does the cerebellum develop?

A
  • in utero but also:
  • cerebellum grows 4x its size in the 1st year of life’

=> humans are born highly underdeveloped.

22
Q

Which part of the spinal cord do spinal cord injuries then to affect?

A
  • sacral and lumbar regions
  • these are more lateral segments on the spinal cord and therefore more likely to be damaged
  • makes sense in a protective way: you need thoracic and cervical for functions like breathing
23
Q

What are some common problems in child development?

A

Delayed walker

Clumsy child

Delayed speech and language

Odd social interaction- ASD/Aspergers

Hyperactivity

Common behaviours – 
sleep onset/freq night 
- waking 
- eating
- Toileting
24
Q

Possible timings of factors that affect child development

A

Prenatal
Perinatal
Postnatal

25
Q

Name some factors influencing developmental delay

A
  • ill health
  • lack of physical/psychological stimulation
  • reduced inherent potentiaal
  • sensory/motor impairment
26
Q

What are the types of developmental delay?

A
  • global

- specific (language, sensory, motor, cognitive)

27
Q

What are some causes of global developmental delay?

A
  • Chromosomal abnormalities
    e. g. Down’s syndrome, Fragile X
  • Metabolic
    e. g. hypothyroidism, inborn errors of metabolism
  • Antenatal and perinatal factors
    Infections, drugs, toxins, anoxia, trauma, folate def
  • Environmental-social issues
  • Chronic illness
28
Q

Causes of motor delay

A
  • Cerebral palsy
  • Global delay eg Down’s syndrome
  • Congenital dislocation hip
  • Social deprivation
  • Muscular dystrophy-Duchenne’s
  • Neural tube defects: spina bifida
  • Hydrocephalus
29
Q

Causes of language delay

A
  • Hearing loss
  • Learning disability
  • Autistic spectrum disorder
  • Lack of stimulation
  • Impaired comprehension of language
    • Developmental dysphasia
  • Impaired speech production
    • stammer, dysarthria
30
Q

What is important to consider when assessing a child?

A

PARENTS KNOW SOMETHING IS WRONG BEFORE PROFESSIONALS DO

31
Q

Approach to developmental assessment

A

ask -> observe -> task

Need to assess

  • Milestones preceding age
  • Expected milestones for age
32
Q

Evaluating the child with abnormal development

A

History

  • Parental anxiety
  • Birth history
  • FHx

PMHX

  • Developmental history
  • Current skills

Examination
- Developmental assessment, + general and neurological examination

Investigations – as appropriate

33
Q

Commonly used assessment tools

A

Standardised tests „

Schedule of Growing Skills (II) „

Griffiths developmental scale „

Bailey developmental scale „

Denver developmental screening tests

OFFER THE RIGHT TOOLS, OBSERVE, LISTEN

34
Q

Focussed Physical examination

A
Look of child
Growth
OFC
Hearing and vision
Skin
Genitalia
35
Q

Blood and imaging examination in developmental problems

A
FBC and ferritin
TSH
Chromosomes
Lead
US
CT/MRI
36
Q

Hormonal problems in growth

A
  • lack of GH

- lack of thyroid hormones

37
Q

What are the objectives of management in developmental problems?

A
  • Maximise mobility
  • Minimise discomfort
  • Promote speech and language
  • Promote social and emotional health
38
Q

What is the role of the MDT in child development?

A

Assessment

Diagnosis and disclosure

Management programme

Social support

39
Q

Who is in the MDT in child development?

A
  • paediatrician
  • OT
  • GP
  • PT
  • SALT
  • social services
  • school nurse
  • Ed psychologist
  • SENCo
  • support groups
  • specialists (neuro, oto, cardio, genetics, psych, opthalmo, surgeons)
40
Q

What fraction of IUGR/SGA babies catch up?

A

85%

41
Q

examples of causes for monogenic obesity

A
  • MCR4R def
  • leptin def (easy to treat)
  • leptinR def
  • …….
42
Q

What is poor growth associated with?

A

increased morbidity and mortality.

43
Q

Moro reflex

A
  • infantile reflex that develops between 28-32w of gestation
  • disappears between 3-6 months of age
  • It is a response to a sudden loss of support (e.g. letting heard drop) and involves three distinct components: spreading out the arms (abduction) pulling the arms in (adduction) crying (usually)
44
Q

regression in terms of development

A
  • loss of skills that were previously acquired and present

- this is worrying