Child/Adolescent Psychiatry Flashcards
What are Genome Wide Association Studies used for?
To identify genetic risk factors for psychiatric disorder
What intra-uterine/perinatal factors may contribute to mental health?
- Maternal health – Maternal antibodies, obesity, diabetes
- Substance misuse – alcohol, marijuana
- Toxins – lead, mercury and PCB’s
- Drugs - esp psychotropics/antiepileptics (lipid soluble)
- Epigenetics – folate controlled methylation
- Endocrine environment – esp androgens
- Immune environment
- Premature birth/ Perinatal complications
- Twinning
What condition is low white matter connectivity associated with?
ADHD
What environmental factors during childhood may affect mental health?
- Carer - child relationship
- Parenting skill and parental mental disorder
- Marital harmony, family function.
- Nutrition, poverty, deprivation.
- Abuse, neglect,
- Discipline
- Day-care and schooling
- Peer relationships,
- Life events,
- Physical disability
What does stress influence in the brain?
- Influences function of limbic circuit (Amydala)
- Determines subsequent patterns of stress response
- Influences mood and patterns of response to threat
What does operant condition refer to?
Dopamine neurons fire when you associate an action with a subsequent reward
What does early adversity do to dopamine response?
Reduces dopamine response
What model is thought to contribute to reward seeking behaviours - ‘addiction’ - later in life?
Reward deficiency model
AKA Hypoactive Reward Response
What model is thought to help explain ADHD?
Delay-aversion and delayed gratification
Roughly what age does intentional smiling begin?
6 weeks
Roughly what age are we able to recognise and label emotions?
24 months
Roughly what age do we exhibit self-awareness of emotion?
3-4 yrs
What is a test of the ability to understand false belief?
Theory of mind
Failure to understand this commonly seen in ASD
What biological factors contribute to child psychiatric illness?
- Genetic predispositions
- Neurodevelopmental Insults
- Illness
What psychological factors contribute to child psychiatric illness?
- Attachment style
- Psychological attributes (Impulsivity, low self esteem, perfectionism)
- Belief system