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Pharm 6 > CHF > Flashcards

CHF Flashcards

1
Q

Milirnone

A

Phosphodiesterase Inhibitor

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2
Q

Dobutamine

A

Adrenoreceptor Agonist

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3
Q

Milirnone Effects

A

Increased Contractility

Vasodilate

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4
Q

Dobutamine Effects

A

Increased CO

Stimulate Beta 1 Receptors

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5
Q

When to use Milirinone

A

ACUTE CHF or EXACERBATION

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6
Q

ADR Milirinone

A 
TOXIC
N/V
Arrhythmia
low platelet
change in liver enzymes
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7
Q

When to use Dobutamine

A

HF if you need to raise BP

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8
Q

Dobutamine ADR

A

Tchy
Angina
Arrhythmia

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9
Q

Furosemide

A

Loop Diuretic

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10
Q

Bumetadine

A

Loop Diuretic

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11
Q

Torsemide

A

Loop Diuretic

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12
Q

ADR loop diuretics

A

Hypokalemia
Hypotension
Worsen renal function

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13
Q

Life Prolonging or Not?

Beta Blocker

A

LP

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14
Q

Life Prolonging or Not?

Digoxin

A

NOT LP

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15
Q

Life Prolonging or Not?

Aldosterone Antagonist

A

LP

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16
Q

Life Prolonging or Not?

Diuretics

A

NOT LP

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17
Q

Life Prolonging or Not?

ACE-I and ARBs

A

LP

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18
Q

Life Prolonging or Not?

Hydralizine

A

LP

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19
Q

Life Prolonging or Not?

Isosorbide

A

LP

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20
Q

Prime Loop Diuertic?

A

Metaxalone

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21
Q

MOA Aldosterone Antagonist

A

Increased Na excretion
Decreased K excretion
less fluid retention

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22
Q

When to use Aldosterone Antagonist

A

POST- MI

23
Q

What drug to use with Aldosterone Antagonist

A

Pt already on ACE-I

24
Q

Aldosterone Antagonist ADR

A

Gynocomastia and period irregular on Spironolatone

25
Q

Spironolactone

A

Aldosterone Antagonist

26
Q

Eplerenone

A

Aldosterone Antagonist

27
Q

ACE MOA

A 
block RAAS
Dilation
Decreased edema
DECREASED REMODELING
***WONDER DRUG!!
28
Q

ADR ACE

A 
hyperkalemia
COUGH
hypotension
renal failure
Angioedema
TERATOGEN!!*!*!*!*
29
Q

-pril

A

ACE

30
Q

Who should be on ACE?

A

EVERYONE WITH CHF (except preg)

31
Q

-sartan

A

ARB

32
Q

ADR ARBs

A 
hyperkalemia
hypotension
renal failure
LESS cough and Angioedema
TERATOGEN!!*!*!*!*
33
Q

Hydralazine MOA

A

Arterial Vasodilator
REDUCE AFTERLOAD
decrease remodeling

34
Q

Isosorbide MOA

A

Venous dilator
REDUCE PRELOAD
decrease remodeling

35
Q

Hydralizine and Isosorbide

A

Vasodilators

36
Q

ADR Vasodilators

A

body compensate:
- tachy
-RAAS
take multiple times a day

37
Q

BiDil

A

Hydralizine and Isosorbide

38
Q

What population is good with BiDil

A

blacks

39
Q

3 BB for CHF

A

Carvedilol
Bisopropilol
Metoprolol Succinate

40
Q

Beta Blocker MOA

A

Decrease SNS activation
Decrease Renin
Decreases cytokine production (fibrosis & V thickness)

41
Q

When to use BB

A

STABLE CHF w/ ACE

42
Q

ARNI

A

Sacubitril/Valsartan

43
Q

Sacubitril/Valsartan MOA

A

S: Decreased vasoconstriction, Decreased Na retention, Decreased remodeling

V: blocks RAAS

44
Q

Sacubitril/Valsartan ADR

A

Hypotension
Hyperkalemia
Angiodema

45
Q

HCN-GCB

A

Ivabradine

46
Q

Ivabradine MOA

A

Selective and Specific
SLOWS SA node firing
Reduce HR

47
Q

When to use Ivabradine

A

Stable CHF
LVEF 70 HR
max dose of BB or cannot tolerate BB

48
Q

Digoxin MOA

A

Increased free Ca in systole
Shortens AP
Slow AV conduction

49
Q

What arrhythmia is Digoxin good for?

A

Afib - when CCB and adenosine fail

50
Q

When to treat Digoxin tox with Digibind

A

Seizures or Arrhythmia

51
Q

Digoxin cannot be used for what arrhythmia?

A

WPW

52
Q

Digoxin treatment for GI and CNS

A

HOLD dose and check levels

53
Q

Where do you want electrolytes with digoxin?

A

K - UPPER limit
Ca - LOWER limit
Mg - UPPER limit

Pharm 6 (5 decks)

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