Chest pain and cardiac arrest Flashcards
Life-threatening causes of chest pain
Cardiac: ACS (e.g. STEMI)
Respiratory: Tension pneumothorax
Vascular: Aortic dissection, PE
Other: Oesophogeal rupture (Boorhave)
Common non-life threatening causes of chest pain:
Cardiovascular: Pericarditis, sickle cell crisis
Respiratory: Pneumonia, empyema
Chest wall: MSK, costochondritis, Bony mets, rib fracture
GI: Reflux, oesophogeal spasm, cholecystitis, peptic ulcer, pancreatitis
Other: Herpes zoster, cervical spondylosis
Spondylosis vs spondylolysis vs spondylolisthesis
Spondylosis: Degeneration of annulus fibrosis + osteophyte formation –> compression of spinal cord (common in cervical)
Spondylolysis: Fracture of vertebral arch (pars interarticularis)
Spondylolisthesis: Slippage of one vertebral disc voer another (usually L5/S1 but may occur in cervical)
Forms of ACS
Unstable angina: Chest pain +/- ECG changes, normal troponin
NSTEMI: Chest pain + ST depression/T-wave inversion/biphasic, trop rise (admission, 1h, 3h)
STEMI: Chest pain + ST elevation
Emergency management of ACS
Morphine + anti-emetic (metoclopramide 10mg)
Oxygen (IF HYPOXIC/LVF)
Nitrate: Sublingual, esp if hypertensive/LVF
Asprin 300mg PO
Beta blocker: bisoprolol 2.5mg if no evidence of shock, HF, asthma, heart block
Primary PCI if STEMI
NSTEMI management after MONA
Fondaparinux 2.5mg SC
Ticagrelor 180mg PO (or clopidogrel 300mg PO if low risk)
Bisoprolol 2.5mg if not CI
Chest pain nurse referral + admission + repeat trop at 6h
UA management after MONA
GRACE score >1,5% –> give clopidogrel
Consider fondaparinux
Secondary prevention of ACS
Beta blocker
ACE-inhibitor
Statin
STEMI criteria
ST elevation >2mm in >1 adjacent chest lead
STE >1mm in >! adjacent limb lead
New LBBB
ST depression + tall R-waves in V1-3 (posterior MI)
DON’T WAIT FOR TROPONIN WON’T ENTER CIRCULATION IN INFARCTION
Non-atherosclerotic causes of ACS
Infective: Emboli from endocarditis
Vasculitis
Cocaine
Hyperthyroidism
Severe anaemia
Risk factors leading to ticagrelor vs clopidogrel in NSTEMI
DM
PVD
CKD
Known coronary artery stenosis
age >60
previous stroke, TIA, MI, CABG
Causes of cardiac tamponade
Trauma
Pericarditis
Breast/lung cancer
MI > ruptured ventricle
Signs of cardiac tamponade
Low BP
High JVP, rises with inspiration
Pulse disappears with inspiration
muffled heart sounds
Hx in aortic dissection
Marfan’s, CTD, dilated aortic root
Tearing chest pain radiating to back + down spine
Collapse
O/E in aortic dissection
Focal neurology
L/R BP difference
Widened mediastinum on CXR (definitive is CT aortogram)