Chest Pain Flashcards

1
Q

Which drug class decreases myocardial oxygen demand?

A

B-blockers ;by reducing exercise induced HR

Calcium channel blockers; by reducing myocardial work ?? TPR ??

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2
Q

Which drug class decreases coronary blood flow?

reduces preload by causing pooling in peripheral veins reducing myocardial oxygen demand

A

Nitrates

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3
Q

What is coronary thrombosis?

A

when a plaque in a coronary artery ruptures

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4
Q

Classify and differentiate the causes of chest pain

A
  1. Causes associated with coronary heart disease;
    - Angina - due to myocardial ischaemia
  2. Not aassociated with CHD;
    - Aortic stenosis
    - Hypertrophic obstructive cardiomyopathy
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5
Q

What are the 4 types of angina?

A
  1. Stable - worse with exertion
  2. Unstable - increasing frequency and severity of angina (plaque going from stable to unstable)
  3. Variant (Prinzmetal) - no cause, spontaneous (st elevation). due to intense coronary spasm @ site of atherosclerotic plaque. pain typical at night.
  4. Syndrome X - myocardial ischaemia thus ST depression on ecg. No atherosclerosis. Common in Perimenopausal or post menopausal
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6
Q

What is the triad of findings in syndrome X?

A

Chest pain
Positive exercise test - found st depression
Angiogram of coronary arteries is clear

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7
Q

How long to do ECG for in Prinzmetal angina?

A

24hours - because they may have spasm at night.

ST elevatoin drops back to normal when spasms cease

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8
Q

What is the key to diagnosis of variant angina?

A

History - pain when they go to bed

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9
Q

What is decubitus angina?

A

Angina on lying down. also due to severe coronary artery stenosis; atherosclerosis

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10
Q

What is decubitus angina?

A

Angina on lying down. also due to severe coronary artery stenosis; atherosclerosis

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11
Q

What type of history is not typical of CHD but rather of other types of chest pain?

A

Atypical chest pain
left sided
sharp
not relieved by GTN

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12
Q

What is a typical CHD patient?

A
Middle age man
obese
diabetes
hypertension
smoker

males more at risk than female!

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13
Q

What are the characteristics of angina as opposed to other causes of chest pain?

A

Site - angina is central

Onset - cardiac chest pain is gradual. sudden pain points to musculoskeletal issues (i.e. worse when moving)

Character - dull ache (like a squeezing) as opposed to sharp

Treatment - GTN

Relieving factors - rest

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14
Q

When GTN relieves chest pain, what does this point to?

A

angina

oesophogeal spasms

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15
Q

Crushing chest pain points to?

A

MI

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16
Q

What are the characteristics of MI?

A

3 S’s;

Sudden
Severe crushing chest pain
Sweating

17
Q

What are the characteristics of Aortic dissection?

A

Tearing abdominal/back pain

higher risk group; elderly

18
Q

What are the characteristics of pericarditis?

A

sharp, sudden chest pain

made worse by deep breaths and posture
risks; preceded by viral infection, usually younger people
relieving factors; sitting forward

19
Q

Important questions to ask in hx for all diseases but especially cardiac issues (even if you yourself cant do anything about it)?

A

Previous treatment - can then tell you, i had i.e. stent put in for past MI

How symptoms affecting daily life

Social history - where do you live, what floor? how do you get up to that floor is there a lift?

20
Q

what 50% of MI’s are followed by what?

21
Q

What tests would you order for someone with chest pain history?

A
ECG (resting)
Angiogram
Bloods - Lipid profile
Exercise stress test
Blood pressure
22
Q

What ECG signs point to previous MI?

A

deep Q wave - lead 3

if q wave is present then an inverted t wave supports this more

23
Q

What is the Bruce protocol?

A

The Bruce Protocol is a exercise test where the subject works to complete exhaustion as the treadmill speed and incline is increased. The length of time on the treadmill is the test score.

24
Q

How does MI prognosis relate to the BRUCE protocol?

A

If the patient last longer than 10 minutes prognosis is good (2% chance of mortality)

If not prognosis is bad (9% chance of mortality)

25
When patients are given oestrogen, what length of st segment depression points to myocardial ischaemia + CHD?
depression greater than 1mm. remember syndrome x patients dont have CHD.
26
How is coronary arterography useful in angina?
It is used to risk stratify those with angina to see how extensive the disease is. it is when a catherter/tube are inserted into the coronary artery
27
How do you manage chest pain, if the cause is CHD related?
All of the following together: 1. Risk factor management + education; exercise and comordity management (i.e. diabetes or hypercholesterolaemia). 2. Anti-platelets (aspirin 75 mg) 3. Statin; atrovastatin (consider ezetimibe then pcsk9i if ineffective) If have angina add: 4. Anti-anginal therapies; sublingual GTN 5. BB +- CCB (nifedipine) +- ISMN 6. Revascularisation therapy (CABG or PCI - percutaneous coronary intervention)
28
Name some anti-anginal drugs?
1. Beta-blockers; Atenolol (25mg), bisoprolol (2.5mg) 2. Calcium antagonists; - Diltiazem, verapamil - Dihydropyridines - 'dipines' - amlodipine. 3. Nitrates; GTN, long acting nitrates (ISMN, ISDN) 4. Nicorandil (note aspirin is NOT part!)
29
Why dont we use DHPs alone for angina?
Cuases reflex tachycardia | so not monotherapy! combined with beta blockers
30
go read missing slides too long ffs
okay
31
Symptoms of aortic stenosis?
breathless on exertion chest pain syncope
32
In stable angina, which therapy improves long term mortality?
Atorvastatin