Chest Flashcards
- Which of the following are correct regarding Adult respiratory distress syndrome (ARDS):
(a) CXR is usually normal in the first 24 h.
(b) The lung is uniformly abnormal on CT.
(c) Has 50% mortality.
(d) The most common CT abnormality in survivors in a reticular pattern.
(e) Bronchial dilatation is seen frequently on CT.
Answers:
(a) Correct
(b) Not correct
(c) Correct
(d) Correct
(e) Correct
Explanation:
Lung involvement is heterogeneous with a gradient density. Dependent lung is more densely opacified than nondependent lung.
- Which of the following are correct regarding pulmonary disease in AIDS patients: (T/F)
(a) Lymphocytic interstitial pneumonia usually progresses to lymphoma in children.
(b) Bilateral perihilar infiltrates on CXR are diagnostic of Pneumocystis Carinii pneumonia.
(c) The presence of Cytomegalovirus in bronchoalveolar lavage fluid indicates active infection.
(d) Lymphadenopathy is seen in <5% of cases of Kaposi’s sarcoma.
(e) Thick-walled cavities are a common HRCT finding of invasive pulmonary aspergillosis.
Answers:
(a) Not correct.
(b) Not correct.
(c) Not correct.
(d) Not correct.
(e) Correct.
Explanation:
Bilateral perihilar infiltrates are a non-specific findings seen in other opportunistic infections as well like CMV and Kaposi’s sarcoma. On HRCT, PCP is most commonly seen as bilateral, symmetric, patchy or confluent ground glass opacity. Less common findings on CXR and HRCT include focal areas of consolidation, mass lesions, multiple lung nodules, pleural fluid, pneumothorax, cavitation, lymphadenopathy and occasional nodal calcification.
CMV is the most common viral pathogen to cause morbidity and mortality in patients with AIDS. The HRCT findings are heterogeneous and include bilateral ground glass opacities, multiple nodules or mass like areas of consolidations and patchy bilateral consolidation.
Pulmonary KS occurs in 18% to 50% of patients with known cutaneous KS and can affect the lung parenchyma, pleural or tracheobronchial tree. Bilateral perihilar pulmonary infiltrates is the most common finding. Other common findings include intralobular septal thickening, lymphadenopathy and pleural effusion.
Lymphocytic interstitial pneumonia is a lymphoproliferative disorder seen with increased frequency in mainly children affected by AIDS. It is mostly benign and regresses spontaneously or with treatment.
@# 5. Which of the following are correct about pulmonary sarcoidosis: (T/F)
(a) Normal CXR excludes the diagnosis.
(b) The large airways are involved in 4-5% of cases.
(c) Subcarinal lymph nodes are characteristically spared.
(d) Fibrosis occurs predominantly in the lower zones.
(e) Pleural effusion is common CXR.
Answers:
(a) Not correct.
(b) Correct
(c) Not correct
(d) Not correct
(e) Not correct
Explanation:
Between 5% to 15% of patients have a normal CXR when first examined.
Pleural effusion is a rare finding (2%).
All mediastinal lymphnodes can be affected in sarcoidosis.
On CT 50% of cases show enlarged subcarinal lymphnodes.
Middle and upper zone fibrosis is characteristic
- Which of the following are correct regarding Langerhans’ cell histiocytosis. (T/F)
(a) Primarily affects cigarette smokers.
(b) Predominantly affects the lung bases.
(c) Most patients are asymptomatic.
(d) Nodular lesions frequently cavitate.
(e) Lung volumes are reduced.
Answers:
(a) Correct
(b) Not correct
(c) Not correct
(d) Correct
(e) Not correct
Explanation:
LCH mostly involves upper and mid zones with relative sparing of lung bases and characteristic appearance of bilateral nodular and reticulo-nodular areas. Most patients are symptomatic with non-productive cough and/or dyspnoea. Lung volumes are characteristically normal or increased.
- When a mass-like lesion is seen on CT, which of the following findings support the diagnosis of rounded atelectasis. (T/F)
(a) An anteromedial location of the mass.
(b) An acute angle with the pleural margins.
(c) Localized crowding of the pulmonary vasculature.
(d) Adjacent pleural thickening.
(e) Absence of enhancement following intravenous contrast.
Answers:
(a) Not correct
(b) Correct
(c) Correct
(d) Correct
(e) Not correct
Explanation:
Round atelectasis is usually seen in posterior or basal region of lower lobes and appears as a well-defined oval or round mass in subpleural location. On Ct the mass shows uniform post intravenous contrast enhancement.
- Which of the following are true regarding silicosis? (T/F)
(a) It predominantly affects the lower lobes in acute silicoproteinosis.
(b) Emphysema is associated with the development of progressive massive fibrosis.
(c) It mimics sarcoidosis on high resolution computed tomography (HRCT).
(d) It is a more frequent cause of nodal egg-shell calcification on radiograph than coal miner’s pneumoconiosis.
(e) Impairment of the lung function test correlates best with the profusion of nodules.
Answers:
(a) Not correct
(b) Correct
(c) Correct
(d) Correct
(e) Not correct
Explanation:
Acute silicoproteinosis has mid and upper zone predominance occurs from intense exposure to silica dust resulting in alveolar exudates. Impairment of the lung function test correlates best with the degree of emphysematous change. Nodular perfusion is a weaker independent correlate.
- Which of the following are true regarding usual interstitial pneumonitis (UIP)? (T/F)
(a) It is more common in females than males.
(b) It occurs most frequently in the sixth decade of life.
(c) It is the most common cause of cryptogenic fibrosing alveolitis.
(d) Areas of ground glass attenuation on HRCT in the absence of parenchymal distortion indicate reversibility.
(e) A confident diagnosis cannot be made on HRCT without lung biopsy.
Answers:
(a) Not correct
(b) Correct
(c) Correct
(d) Correct
(e) Not correct
Explanation:
UIP has no gender predilection.
On HRCT temporal heterogeneity is characteristic of UIP and it refers to different areas of lung demonstrating different stages of inflammation and fibrosis at the same time. This helps to make confident diagnosis in majority of the cases
- Which of the following are correct regarding Goodpasture’s syndrome: (T/F)
(a) Hilar lymph nodes may be enlarged.
(b) Changes are commonly unilateral.
(c) Prognosis is good.
(d) Acute presentation is with air-space consolidation typically at the lung apices.
(e) Signs of renal failure precede pulmonary complaints.
Answers:
(a) Correct
(b) Not correct
(c) Not correct
(d) Not correct
(e) Not correct
Explanation:
Goodpasture’s syndrome is bilateral with poor prognosis and death usually within 3 yrs of diagnosis. Pulmonary involvement is before renal involvement with relative sparing of lung apices.
- Which of the following are correct regarding lymphangioleiomyomatosis (LAM): (T/F)
(a) Pulmonary abnormalities are similar to those seen in tuberous sclerosis.
(b) It is found exclusively n females.
(c) Cysts commonly have a bizarre outline.
(d) Cysts show sparing of the apices.
(e) There is an association with chylothorax.
Answers:
(a) Correct
(b) Correct
(c) Not correct
(d) Not correct
(e) Correct
Explanations:
In LAM cysts are usually uniform and round with uniform distribution. Cysts in LCH have bizarre irregular outlinesand show apical sparing.
- Which of the following are correct regarding lymphangioleiomyomatosis (LAM): (T/F)
(a) Pulmonary abnormalities are similar to those seen in tuberous sclerosis.
(b) It is found exclusively n females.
(c) Cysts commonly have a bizarre outline.
(d) Cysts show sparing of the apices.
(e) There is an association with chylothorax.
Answers:
(a) Correct
(b) Correct
(c) Not correct
(d) Not correct
(e) Correct
Explanations:
In LAM cysts are usually uniform and round with uniform distribution. Cysts in LCH have bizarre irregular outlinesand show apical sparing.
- Causes of eggshell calcification of lymph nodes include: (T/F)
(a) Rheumatoid arthritis.
(b) Silicosis.
(c) Scleroderma.
(d) Histoplasmosis.
(e) Amyloidosis.
Answers:
(a) Not correct
(b) Correct
(c) Correct
(d) Correct
(e) Correct
Explanation:
Rheumatoid arthritis rarely shows lymphnodal calcification.
- Features of pulmonary asbestosis include: (T/F)
(a) Increased severity in sub-pleural zones.
(b) Hilar adenopathy.
(c) Upper lobe massive fibrosis.
(d) Thickened interlobular septa on HRCT.
(e) Increased incidence of bronchio-alveolar cell carcinoma.
Answers:
(a) Correct
(b) Not correct
(c) Not correct
(d) Correct
(e) Correct
Explanation:
Asbestosis shows lower lobe fibrosis with no hilar lymphadenopathy.
- Which of the following are correct regarding HRCT features of pulmonary alveolar proteinosis (PAP): (T/F)
(a) Usually shows a lower zone distribution.
(b) Pleural effusion is common at presentation.
(c) Lymphadenopathy is a common feature.
(d) Regions of emphysema are commonly observed.
(e) Crazy paving pattern is a specific feature
Answers:
(a) Correct
(b) Not correct
(c) Not correct
(d) Not correct
(e) Not correct
Explanation:
Pleural effusion is rare in untreated PAP.
Lymphadenopathy is uncommon.
Crazy paving pattern though suggestive of PAP, is also seen in ARDS, acute interstitial pneumonia and drug induced pneumonias
- Which of the following are correct regarding extrinsic allergic alveolitis (EAA): (T/F)
(a) A normal CXR excludes the diagnosis.
(b) Smoking is a risk factor.
(c) The upper zones are typically involved in acute EAA.
(d) Ground-glass opacity is a characteristic HRCT finding.
(e) Bronchiectasis is seen on HRCT in chronic EAA
Answers:
(a) Not correct
(b) Not correct
(c) Not correct
(d) Correct
(e) Correct
Explanation:
CXRs are generally normal in patients with mild symptoms and in some cases with severe symptoms.
Smokers are protected from EAA also called hypersensitivity pneumonitis.
The most common forms are farmer’s lung and bird fancier’s lung.
Typically mid to lower zones are affected with sparing of costophrenic angles.
Presentation is like pulmonary oedema with bilateral areas of increased opacity that may be heterogeneous or homogeneous.
- Which of the following are true regarding cryptogenic organising pneumonia (COP)? (T/F)
(a) The disease is rarely symptomatic.
(b) An obstructive pattern of lung function impairment is typical.
(c) Pleural effusions are common.
(d) Radiographic clearing occurs following steroid treatment.
(e) Bilateral basal peripheral consolidation is a common radiographic finding
Answers:
(a) Not correct
(b) Correct
(c) Not correct
(d) Correct
(e) Correct
Explanation:
50% of the patients are symptomatic presenting with fever, cough, breathlessness and malaise with peak incidence in5th and 6th decades of life. COP is also known as BOOP (bronchiolitis obliterans organizing pneumonia) or bronchiolitis obliterans with intramural polyps.
Pleural effusion is uncommon (5% cases