Chemotherpy Flashcards
Types of cancer therapies
Chemotherapy
Personalises
Target
Immunotherapy
Types of chemotherapy
Alkylating agents
Antimetabolites
Organic
Examples of alkalating agents
Cyclophosphamide
Carboplatin
How to Alkalating agents work
Coventry bond alkyine groups to dna causing cross linked and dna adducts means no replication caring cell arrest
What phases does it effect
All phases
Antimetabolites
Effect by either replacing nucleotide or inhibiting enzymes for t
Examples of Antimetabolites
5-fu and methotrexate 
Organic types
Microchip inhibitors and anticylins (antibiotics)
Mitotic inhibitors
Vinca alkaloids - periwinkle plant - vincristine
Taxances
Anticyclins examples
Dexorubin epirubin
How to antibiotics for a canter work
Topolymerase 2
Receptors that cause nausea and vomiting
Nk1 and 5ht3
Drugs that help with vomiting
ODAN- steron
APREP-riant
Personalised - hormonal therapy
Temoxofrin binds to receptors osterogen growth ones Brest cancer
Lextrozole Aromatase inhibitor
Targeted
ECG
Vegf