Chemotherapy - cancer and malignancy Flashcards
1) Give the clinical use of platinum compounds in urological cancers.
2) Name the P drug which is a platinum compound.
1) Metastatic urothelial tumours in combination chemotherapy.
2) Cisplatin.
1) In urology, what are tyrosine kinase inhibitors and tyrosine kinase receptor inhibitors used for?
2) Name the 2 P drugs which are tyrosine kinase inhibitors/ tyrosine kinase receptor inhibitors.
1) Advanced renal cell carcinomas.
2) Sunitinib and Bevacizumab
Name the 2 types of drugs which are used for metastatic prostate cancer and give the P drugs examples for each.
1) Gonadorelin analogues (Goserelin)
2) Anti-androgens (Cyproterone acetate)
Name the 2 P drugs which are alkylating agents.
Cyclophosphamide and Chlorambucil
Name the 2 P drugs which are cytotoxic antibiotics.
Doxorubicin and Bleomycin
Name the 3 P drugs which are platinum compounds.
1) Carboplatin
2) Cisplatin
3) Oxaliplatin
What class of drug is methotrexate?
Folate antagonist.
Name the 2 P drugs which are base analogue metabolites.
Mercaptopurine and Capecitabine
What class of drug is Vincristine?
Vinca alkaloid.
1) Name the P drug which is a Camptothecin analogue (topoisomerase I inhibitor).
2) Name the P drug which is a Epipodophyllotoxin (topoisomerase II inhibitor).
1) Topotecan
2) Etoposide
1) What class of drug is Docetaxel?
2) What class of drug is Bevacizumab?
3) What does Imatinib do?
1) Taxane.
2) Tyrosine kinase receptor inhibitor.
3) Inhibits tyrosine kinases and other protein kinases.
Name a P drug for each of the following classes of chemotherapy agent:
1) Proteasome Inhibitors
2) Oestrogen receptor antagonists
3) Aromatase inhibitors
4) Androgen receptor antagonists
5) Gonadorelin analogues
1) Bortezomib
2) Tamoxifen
3) Anastrazole
4) Flutamide
5) Buserelin/ Goserelin
