Chemotherapy Flashcards

1
Q

Radiosensitizer

A

Doxorubicin (Adriamycin)
Can cause Cardiac Toxicity

Cisplatin
Can cause hearing loss, nephrotoxicity

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2
Q

Radioprotector

A

Amifostine

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3
Q

Bleomycin

A

Can cause Pulmonary Toxicity

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4
Q

Vinka Alkaloids (Mitotic Inhibitors)

A

Periwinkle Plant
Terminates Cell Replication in Metaphase

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5
Q

Topoisomerase Inhibitors

A

Plant Alkaloid
Interferes with Enzymes (topoismerases) to stop replication

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6
Q

Hormonal Agents

A

Replaces natural hormones

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7
Q

Anti-Tumor Antibiotics

A

Hinders transcription of DNA & RNA

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8
Q

Antimetabolites

A

5-FU
Disturbs the formation of new Nucleic Acids
Cell Cycle Specific

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9
Q

Nitrosoureas

A

Group of Alkylating Agents
Hinders the Synthesis of DNA
Can cross BBB (lipid soluble)

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10
Q

Alkylating Agents

A

Chemically similar to Mustard Gas

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