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Meg Surg 200 > Chemo Treatments > Flashcards

Chemo Treatments Flashcards

1
Q

Alkylating Agents Examples

A

” atin & mide” Cyclophosphamide
Carboplatin
Cisplatin
Bendamustine
Oxaliplatin
Temozolomide

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2
Q

Alkylating Agents Side Effects

A

mucositis- mouth sores
alopecia- hair loss
pancytopenia- low WBC, rbc, platelets
sterility

DANGER : ototoxicity, hemorrhagic cystitis

Bad for Nephro and Hepatic

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3
Q

What do Alkylating agents do?

A

DNA damage across ALL cells ( even the good ones)

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4
Q

Nursing intervention for Alkylating Agents

A

Monitor temp
Assess skin + mental staus

Contraindicated with pts with liver, kidney and GI disorders

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5
Q

Antimetabolite Agents Examples

A

” Bine” capecitabine, cytarbine, decitabine, methotrexate, Flurouracil, Azacitidine,hydroxye
Pemetrexed,Lonsurf, Gemcitabine

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6
Q

Antimetabolites function?

A

Disrupt DNA/RNA synthesis during cell division ( S phase)

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7
Q

Antimetabolites side effects

A

Mucositis
AT risk for GI bleed
nausea/ vomiting

DANGER: Nephrotoxic, hepatoxic, pulmonary edema

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8
Q

Antimetabolites nursing interventions

A

Monitor temp-infection
monitory dyspnea and cough
monitor nutrition and fluid intake

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9
Q

Antimetbolities lab monitoring

A

CBC, electrolytes, kindney and LFT

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10
Q

Alkylating agents lab monitoring

A

Monitor cbc, uric acid, kidney and LFT

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11
Q

Antitumor Antibiotics examples

A

” icin” Doxorubicin, Daunorubicin,Dactinomycin, Bleomycin, epirubicin, mitoxantrone, idarubicin, anthracyclines

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12
Q

Antitumor Antibiotic side effects

A

Pancytopenia- decrease in WBC, RBC, Platelets
Alopecia-hair loss
Mucositis,
Pulmonary Fibrosis(Bleomycin)

Cardiotoxic, Hepatotoxic

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13
Q

Antimetabolite PT education

A

Use electric razor
use soft toothbrush
avoid flossing
use shoes- neuropathy

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14
Q

Antitumor Antibiotic Pt Education

A

Doxorubicin: causes red pee

Teach about sterility
Monitoring temp

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15
Q

Antitumor function

A

Alters DNA structure

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16
Q

Antitumor monitor labs

A

CBC and electrolyte

Cardiovascular, respiratory and neurologic status

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17
Q

Topoisomerase inhibitor function

A

stops multiplication and causes the cancer cells to kill themselves

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17
Q

Topoisomerase Inhibitors examples

A

” side & can “ Epoposide, irintecan, topotecan, teniposide

18
Q

Topoisomerase inhibitor side effects

A

Taste changes ( BIG ONE): tell them to eat with a plastic spoon to decrease the metallic taste

Monitor bleeding & infection

access nutritional status

19
Q

Topoisomerase inhibitor nursing intervention

A

Monitor bleeding
Signs of infection
Assess nutritonal and fluid intake

20
Q

Topoisomerase inhibitor lab monitoring

A

CNC and LFT

Monitor neurologic and cardio status

21
Q

Mitotic inhibitors function

A

Stop cancer from growing, may affect other cells as well

By inhibiting mitosis

22
Q

Mitotic inhibitors examples

A

” tine & axel” Vincristine, Vinbilastine panlitaxel, docetaxel, cabazitaxel,

23
Q

Mitotic inhibitors side effects

A

Pancytopenia
Alopenia
mucositis
weight loss, allergic reaction
Peripheral neurpathy

24
Q

Nuring intevention lab monitor

A

CBC and LFT
Montior neurlogic and cardio status

25
Q

Mitotic inhibitors Pt education

A

Neuropathy: assess
what their finger and toes feel like

Nurses want to promote independence

Weight loss

26
Q

Hormonal therapy Types

A

Surgery and Drug therapy

27
Q

What are the 3 things keep in mind about hormonal therapy

A

changes the level of hormones in the body

Complementary therapy

Treatment based on the type of cancer and hormonal status

28
Q

Hormonal therapy meds

A

Anastrezole exemestane, cetrozone tamoxifen (ERPR need to be positive)

Abiraterone, enzalutamide,aromatase inhibitors, leuprolide, goserlin, bicalutamide
coticorsteriods

29
Q

Hormonal Therapy side effects

A

Hot flashes/ night sweats
loss of muscles mass-atrophy
weight change
loss of sex drive
osteoporosis
fatigue
HIGH RISK FOR BLOOD CLOTS, STROKE, MI, UTERINE CANCER

30
Q

Hormonal therapy lab monitoring

A

Monitor CBC and Calcium

31
Q

Hormonal Therapy PT education

A

NOT to stop medication unless directed by provider

weight loss

sex drive is lost

32
Q

Immunotherapy function

A

Help body produce cancer-fighting immune cells

Destroy cancer cells

33
Q

Types of immunotherapy (5)

A

Checkpoint inhibitors
Tcell transfer therapy
Monoclonal antibodies
Cancer vaccines( HPV)
immune system modulators

34
Q

Immunotherapy meds (4)

A

” mide and 1 mod”
Thalidomide
Lenalidomide
Pomalidomide
Imiquimod

35
Q

Immunotherapy side effects

A

Fatigue
rash
diarrhea
Nausea/vomiting
DECREASED THYROID LEVELS

36
Q

Targeted therapy function

A

Blocks signal for cancer growth to prevent it from growing

Stops making new blood vessels to feed cancer cells

Change proteins in cancer cells so they die

Carry toxins to cancer cells

37
Q

Target therapy patho

A

Attacks the EGFR protein

37
Q

Targets therapy side effects

A

May feel burnt
Thinning hair
skin color / hair change to yellow
hypertension
red dry tender eyes
blood clotting problems
cardiac damage
food hand syndrome

38
Q

Targeted therapy monitor

A

Monitor electrolytes
infection
fluid intake
nutrition
capillary leak syndrome
respiratory staus

39
Q

Radiation therapy Function

A

ONLY treatment for cancer

40
Q

Types of radiation (2)

A

external Beam- most common, proton therapy: directed on the tumor

internal- brachytherapy( implanted prostate, cervical or vaginal), gamma knife( head, neck)

41
Q

radiation therapy types ( 2)

A

Neoadjuvant therapy- Before surgery to shrink the tumor

Adjuvant Therapy- Post-surgical to stop the growth of remaining cancer cells

Meg Surg 200 (4 decks)

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