Chemo Drugs Flashcards
Vidaza
IV
For bone marrow and blood cancers Antimetabolite Route: IV Side Effects: decreased vitamin K levels n/v/d/f
Vectibix
IV
For metastatic colon cancer
Monoclonal EGFR sensitive
Side Effect: D/low magnesium
Sutent
(oral)
GIST, renal pancreatic, neuroendrocrine
Protein Targeted therapy
SE: n/v/d/decreased appetite, hand-foot sx, rash, can turn hair white
NO GRAPEFRUIT
Epirubin (Ellence)
IV
Breast
Antitumor ATB- Cell Cycle Specific
SE: N/V/D/mucositis/rash
Gemzar
IV
Pancreatic/bladder/breast/ovarian/lung
Antimetabolite-Cell Cycle Specific (pyrimide antagonist)
SE: n/v/pulmonary/flu like sx/clay colored stools
Cytoxan (cyclophosphamide)
IV
Breast, ovarian, CLL, lymphomas Alkylating Agent (non cell cycle specific) SE: BLADDER TOXICITY, N/v PUSH FLUIDS Give Mensa to prevent bleeding cysts Can increase effect of anticoagulants
Taxol (paclitaxel)
IV
bladder, breast, ovarian, H&N, Esophageal, lung, prostate pancreatic Plant Alkaloid(taxane) SE: diarrhea/Mucositis
Doxil (doxorubin liposomal)
IV
Metastatic ovarian, Kaposi’s, breast
Antitumor ATB
SE: n/v/d/mucositis, hand foot sx
turns urine red
Adriamycin(doxorubin)
IV
breast, gastric, HN, lung, liver, kidney ALL and many more
Anthracycline ATB
SE: n/v/d/mucositis/hand foot sx, anorexia, “red devil”
Give Omega 3s/CoQ 10/Theanine- may reduce toxicity
Vinorelbine(navelbine)
IV
breast, ovarian, lung
Plant alkaloid
SE: constipation, stomatitis
a/n/v
Etoposide
IV
lung, gastric, testicular, bladder prostate
Plant Alkaloid (cell cycle specific)
SE: Metallic taste, a/n/v/d
Herceptin (Trastuzumab)
IV
metastatic breast cancer HER2/NEU
Monoclonol ATB
SE: n/v/d
avocados, olive oil increase sensitivity to drug
xgeva (denosumab)
injection
To prevent skeletal related events
Monocolonal ATB RANK inhibitor
SE: n/v/d, decreased Calcium
Osteonecrosis of jaw
Carboplatin (paraplatin)
IV
HN, bladder, ovarian, lung endo
Alkylating agent
SE: n/v, peripheral neuropathy
Treanda (bendamustine)
IV
CLL, NHL
Alkylating agent
SE: n/v/f
Tumor lysis syndrome
Iressa
oral
NSCLC
Protein target tx- tyrosine kinase inhibitor EGFR
SE: n/v/d, decrease appetite, hand-foot sx
Take with WATER
Kadcyla
IV
HER2+ metastatic breast
Monoclonal ATB
SE: Constipation, increased liver enzymes, n/f
List 3 Aromatase Inhibitors
Anastrozenole (Arimidex)
Aromasin(exemestane)
Femara
SE: hot flashes, fatigue, joint pain, blood clots, muscle aches, elev. chol, BONE LOSS
AntiEstrogens
Counsel to promote bone strength (calcium, vit D, exercise)
Zometa
IV
bone mets
Need 500 mg Calcium and 400 IU Vit D daily
Vincristine (oncovin)
IV
leukemia, lymphoma, Multiple Myeloma, brain
Plant Alkaloid (cell cycle specific)
SE: SEVERE CONSTIPATION, Jaw pain, decreased appetite
AVOID: SJ WORT, GRAPEFRUIT
Vinblastine (Velban)
IV
breast, testicular, HN, lymphoma
Plant Alkaloid (cell cycle specific)
SE: mucositis, stomatitis, severe constipation, jaw pain
AVOID: SJ WORT, GRAPEFRUIT
TORISEL
oral
advanced renal cell
mTOR inhibitor
SE: hyperglycemia, elevated cholestrol