Chemistry: Lipids and Lipoproteins Flashcards

1
Q

Lipoprotein that has the most amount of lipid content.

a. HDL
b. Chylomicron
c. VLDL
d. HDL

A

HDL

(Self-made)
Reference: Bishop

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2
Q
  1. Which of the following methods for lipoprotein electrophoresis depends on charge and molecular size?

a. Polyacrylamide gel
b. Paper
c. Cellulose acetate
d. Agarose

A

Polyacrylamide gel

Reference: Bishop

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3
Q

Which of the following statements concerning chylomicrons is FALSE?

a. The major lipid transported by this lipoprotein is cholesterol.
b. This lipoprotein is produced in the intestinal mucosa.
c. The primary function is to carry dietary (exogenous) lipids to the liver.
d. It remains at the origin (point of application) during lipoprotein electrophoresis.

A

The major lipid transported by this lipoprotein is cholesterol.

Bishop

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4
Q

The lipoprotein that contains the greatest amount of protein is called

a. HDL
b. Chylomicrons
c. VLDL
d. LDL

A

HDL

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5
Q

True or False? Pre-beta (VLDL) lipoproteins migrate further toward the anode on polyacrylamide gel than they do on cellulose acetate or agarose.
a. True
b. False

A

FALSE

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6
Q

In the colorimetric determination of cholesterol using the enzyme cholesterol oxidase, the agent that oxidizes the colorless organic compound 4- aminoantipyrine to a pink complex is
a. Hydrogen peroxide
b. Cholest-4-ene-3-one
c. NAD
d. Phenol

A

Hydrogen Peroxide

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7
Q

A patient is admitted to the hospital with intense
chest pains. The patient’s primary care physician requests the emergency department doctor to order several tests, including a lipid profile with cholesterol fractionation. Given the patient’s results provided below, what would be the LDL-C for this patient?

Total cholesterol = 400 mg/dL; triglycerides = 300 mg/dL;
HDL-C = 100 mg/dL;
LP electrophoresis, pending

a. 240 mg/dL
b. 160 mg/dL
c. 200 mg/dL
d. 300 mg/dL

A

240 mg/dL

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8
Q

Which of the following results is the most consistent with high risk of CHD?
a. 20 mg/dL HDL-C and 250 mg/dL total cholesterol
b. 35 mg/dL HDL-C and 200 mg/dL total cholesterol
c. 50 mg/dL HDL-C and 190 mg/dL total cholesterol
d. 55 mg/dL HDL-C and 180 mg/dL total cholesterol

A

a. 20 mg/dL HDLc and 250 mg/dL total cholesterol

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9
Q
  1. Hyperchylomicronemia (type I) in childhood has
    been associated with which of the following?

a. A deficiency of apo C-II
b. A deficiency of LCAT
c. A deficiency of LPL
d. A deficiency of apo A-I

A

a. A deficiency of apo C-II

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10
Q

considered as the simplest lipid

A

NEFA
(Non-Esterified Fatty Acid)

Module

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