Chemical restraint

Question 1

if CRi is used, a loading dose should be considered; otherwise the desired effects will take a protracted time because __ to __ half-lives are needed until steady state plasma concentrations and sedation are reached.

Answer 1

4 to 5

Question 2

T/F: the increased sensitivity to touch reported clinically with α2-adrenoreceptor agonists may be induced by modification of the activity of fast conducting non-nociceptive afferent Aβ fibers and seems to be strongest and longest with detomidine compared to romifidine and xylazine.

Answer 2

True

Question 3

T/F: Potentiated sulfonamides should never be administered IV following α2-adrenoreceptor agonists, as fatal arrhythmias might occur.

Answer 3

True

Question 4

the phenothiazines exert their tranquilizing effect primarily by blocking __________ receptors in the basal ganglia and limbic system.

Answer 4

dopamine

Question 5

____________ produce their pharmacologic effects by facilitating the actions of γ-aminobutyric acid (GABA), the principal inhibitory neurotransmitter in the central nervous system.

Answer 5

Benzodiazepines