chelating Agents Flashcards
1
Q
Dimercaprol
A
Monotherapy for acute arsenic/mercury poisoning
Combo therapy with edetate
contraindicated for use alone after CHRONIC exposure to lead, since lead will invade CNS
2
Q
Succimer, Unithiol
A
Next gen dimercaprol-related chelators.
Wider indeces
3
Q
Succimer
A
water soluble form of dimercaprol
use with pb toxicity
Very safe
4
Q
Edetate Calcium Disodium
A
FDA approved for Pb poisoning
IV
CONTRA in anuric patients, or kidney feilure
5
Q
Unithiol
A
water soluble form of dimercaprol
Oral or IV
NOT FDA approved for indications
6
Q
Cyanide
A
inhibits Cytochrome C, No ATP
Hydrogen cyanide most toxic
7
Q
Hydroxycobalamin
A
reacts with Cyanide.
Antidote