chelating Agents Flashcards

1
Q

Dimercaprol

A

Monotherapy for acute arsenic/mercury poisoning

Combo therapy with edetate

contraindicated for use alone after CHRONIC exposure to lead, since lead will invade CNS

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2
Q

Succimer, Unithiol

A

Next gen dimercaprol-related chelators.

Wider indeces

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3
Q

Succimer

A

water soluble form of dimercaprol

use with pb toxicity

Very safe

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4
Q

Edetate Calcium Disodium

A

FDA approved for Pb poisoning

IV

CONTRA in anuric patients, or kidney feilure

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5
Q

Unithiol

A

water soluble form of dimercaprol

Oral or IV

NOT FDA approved for indications

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6
Q

Cyanide

A

inhibits Cytochrome C, No ATP

Hydrogen cyanide most toxic

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7
Q

Hydroxycobalamin

A

reacts with Cyanide.

Antidote

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