Chapter1 Flashcards

1
Q

How does the endocrine system’s cells communicate?

A

Uses chemical messengers to relay information and instructions btwn cells

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2
Q

Difference btwn nervous system and endocrine system

A

NS: uses electricity and chemicals to send a fast message
Has a specific effector organ
ES: uses hormones
Effects many effector organs (high to all muscles)
Is slower and longer lasting

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3
Q

Difference btwn neurotransmitters and hormones

A

NT: are released by neurons
Talk to effector organs (i.e ACh)
Only work if there is a receptor in cell inhibitor =GABA
Hormones: are released by endocrine glands
Released in blood
Need receptors for it to affects the cell

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4
Q

How does negative feedback play a role in hormones?

A

Responses to changed body condition
If high or low from normal level
Signal tells body to make changes that will bring body back to normal level
Once body goes back, the signal is turned off

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5
Q

3 types of intercellular communication

A

Direct, parachute, endocrine

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6
Q

Direct communication

A

Exchange of ions and molecules btwn gap jxns
2 cells of the same type
Cardiac cells

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7
Q

Paracrine communication

A

Uses chemicals signals to transfer info
Within single tissue
Most common form

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8
Q

Endocrine communication

A
Release chemicals (hormones) into bloodstream
Needs a receptor
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9
Q

3 types of hormones

A

Amino acid derivatives
Peptide hormones
Lipid derivatives

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10
Q

Free hormones

A

Remain functional for less than 1 hour

Diffuse out of blood stream and bind to receptors on target cells

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11
Q

Thyroid and steroid hormones

A

Remain in circulation much longer

Enter bloodstream

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12
Q

Lipid soluble hormones

A
Glucocorticoids
Estrogens
Androgens 
Thyroid hormone (T3)
Calcitriol 

Diffuse across the plasma membrane to reach receptor proteins

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13
Q

Hormones that aren’t lipid soluble

A
Prolactin
ACTH
Growth hormone
ADH
Peptide hormones
ANP
ANF
Insulin
Leptin
Unable to penetrate plasma membrane
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14
Q

Hormone receptor

A

Protein molecule to which particular molecule binds strongly different tissues have different combinations of receptors

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15
Q

Hormones and plasma membrane receptors

A

Bind to receptor in plasma membrane
Cannot have direct effect on activities inside target cell
Use intracellular intermediary to exert effects

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16
Q

Second messengers

A
Cyclic-AMP
--> derivative of ATP
Cyclic-GMP
--> derivative of GTP
Calcium ions
17
Q

Amplification

A

Takes something small and makes it bigger
Binding of a small number of hormone molecules to membrane receptors
Leads to many second messengers in cells
Magnifies effect of hormone on target cell

18
Q

Down regulation

A

Presence of hormone trigger decrease in number of hormone receptors
Less sensitive and receptors are all filled up

19
Q

Up-regulation

A

Absence of a hormone triggers increase in number of hormone receptors
More sensitive dreams
Receptors are available

20
Q

What hormones do extra cellular receptors bind to?

A

No lipid soluble protein hormones

21
Q

What hormones does intracellular receptors bind to?

A

Lipid soluble

22
Q

Mechanisms of hormone action

A

Bind to DNA and make messenger RNA

23
Q

Endocrine reflexes

A

Fxnal counterparts of neural reflexes

Mostly negative feeback

24
Q

What riggers endocrine reflexes? Explain each

A

Humoral stimuli: changes in compositions for extracellular fluid
Hormonal stimuli: arrival or removal of specific hormone
Neural stimuli: arrival of NT at neuroglandular jxn

25
Simple endocrine reflex
Involves only one hormone Controls hormone secretion Heart
26
Complex endocrine reflex
Involves one or more intermediary steps Two or more hormones Hypothalamus
27
Neuroendocrine reflexes
Pathways include both neural and endocrine components
28
Complex commands
Issued by changing: Amt of hormone secreted, pattern of hormone released
29
What 3 ways does hypothalamus integrates activities of nervous and endocrine system?
-secrete regulatory hormones: special hormones that control endocrine cells in pituitary gland - acts as an endocrine organ -contains autonomic centers Exert direct neural control over endocrine cells of adrenal medullae
30
Where does the pituitary gland lie? What is it called?
Lies within sella Turcica | Also called hypophysis
31
What are the 2 classes of hypothalamic regulatory hormones? Explain each
Releasing hormones: stimulate synthesis and secretion of one or more hormones at anterior lobe Inhibiting hormones: prevent synthesis and secretion of hormones from the anterior lobe
32
Who does the hypothalamus communicate with and how? (Anterior)
Anterior pituitary gland by releasing IH and RH | Puts these in capillary networks instead of blood
33
How does hypothalamus talk to posterior?
This is neuronal Specialized cells a on goes to posterior pituitary, so 2 hormones made up in hypothalamus, and transported in axons and released from posterior (releases and secretes hormones)
34
What hormones are released by posterior pituitary gland? Explain each
Oxytocin: stimulates contractions during labor ADH: decreases urine production so you don't loose as much water
35
What type of process does the endocrine system regulate?
Regulates long-term processes - growth - development - reproduction