Chapter 99 PV and other MPNs Flashcards

1
Q

The most common of the MPN

A

Polycythemia vera

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2
Q

Most common cytogenetic abnormality in PV

A

Loss of heterozygosity on chromosome 9p

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3
Q

Erythema, burning and pain in the extremities

A

Erythromelalgia

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4
Q

Relative erythocytosis due to a reduction in plasma volume alone

A

Stress or spurious erythrocytosis or Gaisböck’s syndrome

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5
Q

The only 3 situations causing microcytic erythrocytosis

A

B-thalassemia trait
(RDW normal)

Hypoxic erythocytosis

PV

(RDW may be elevated due to associated iron deficiency)

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