Chapter 9.6 Flashcards
Myasthenia Gravis -cause
Autoimmune disease where the Antibodies block Ach receptors
-M.G-Symptoms
Drooping eyelids, DYsphagia (Swallowing), DYsphasia (Speaking), general muscle weakness.
M.G-Treatment
No cure:(, Ach inhibitors and immunosuppressents (corticosteroids).
DMD)-Duchenne Muscular Dystrophy-cause
X-linked disease where the gene for distrophyn is defective.
Symptoms
2-7 boys, goes from extermities to the head and chest. Cognitive difficulty, lessened heart function—heart failure, weakens iaphragm–use of ventilator—Pneumonia, Decreased muscle mass, weak and britle bones.
Treatments-
No cure, STEROIDS to reduce inflammation, and Phys therapy to keep them as mobile as possible
Anaerobic Threshold
Point at which muscle metabolism converts to ANAEROBIC Resp.
Aerobic Endurance
The length of time your muscle can contract while using Aerobic respiration.
Physiological Muscle Fatigue
State of physiological inability to contract even though it is receiving stimulus.
Pseudo/Central/Psychological fatigue
Occurs before physiologicla fatigue. Warning, helps prevent you from getting into Physio fatigue.
Causes of muscle fatigue
Depletion of fuels (CP stores and glycogen), accumulation of K+,
- During brief periods of tetany, tension decreases as large motor units (fast twitch fibers) fatigue.
- Intense short duration exercise produces fatigue rapidly via ionic disturbances that alter Excitation-contraction coupling, but recovery is rapid.
- Slow-developing fatigue of prolonged low-intensity exercise
EPOC
Difference between the amount of Oxygen required if we were to do the whole ting (a full aerobic metabolism) vs the amount of oxygen we actually used.
Physiological reason why we increase muscle tension
Myosin heads binding to Actin
4 Factors that Determine Force of Contraction:
Frequency of Stimulation, Number of motor units/muscle fibers recruited, Size of muscle fibers, Degree of muscle stretch
These all increase the number of cross bridges attached, thus increasing, contractile force.
Describe Aerobic Exercise
3 tings:
a. Exercises like jogging, ect will increase number of myoglobulin, capillaries, mitochondria, ..
b. Consistent Aerobi exercise can convert a few fast glyocolytic fibers to fat oxidative fiers.
c. Overall, it increases the efficiency of muscle metabolism, greater endurance, and resistance to fatigue