Chapter 9 - Microbial Genetics Flashcards
P site
holds the tRNA that carries the growing polypeptide chain
A site
holds the tRNA that carries the next amindo acid to be added to the chain
E site
is the exit site, where discharged tRNAs leave the ribosome
constituitive enzymes
synthesized constantly
inducible enzymes
not routinely produced; synthesize only when needed
repressible enzymes
produced routinely; turned off when not required
spontaenous mutations
random change in the DNA due to errors in replication that occur without known cause
induced mutations
result from exposure to known mutagens, physical (primarily radiation) or chemical agents that interact with DNA in a disruptive manner
point mutation
addition, deletion, or substitution of a base
missense mutation
causes change in a single amino acide
nonsense mutation
changes a normal codon into a stop codon
silent mutation
alters a base but does not change the amino acid
back-mutation
when a mutated gene reverses to its original base composition
frameshift mutation
when the reading frame of the mRNA is altered