chapter 9 Flashcards
Transcription
transfer of genetic information from the base sequence of DNA to the base sequence of RNA, mediated by RNA synthesis
Messenger RNA (mRNA)
A single-stranded complementary copy of the nucleotide sequence in a gene
Alternative splicing
exons from the same gene are joined in different combinations, leading to different, but related, mRNA transcripts
What is the central dogma of molecular biology
A theory stating that genetic information flows only in one direction from DNA to RNA, to protein, or RNA directly to protein
three stages of transcription and what happens in each stage
1.) Initiation: formed by the combination of mRNA, initiation tRNA, and the small ribosome subunit
2.) Elongation: the stage when the RNA strand gets longer, thanks to the addition of new nucleotides
3.) Termination: begins when a polyadenylation signal appears in the RNA transcript
How alternative splicing affects the expression of genes
Causes several human genetic disorders