Chapter 9

Question 1

Which disorder describes the following:

Bleeding Time or PFA: normal
PT: normal
APTT: prolonged
Confirmed with: Factor assay VIII

a) Hemophilia A
b) Hemophila B
c) Hemophila C

Answer 1

Hemophilia A

(Hemophilia A has a deficiency of factor VIII, its pathway is part of the intrinsic pathway, so the APTT would be prolonged. The bleeding time would be normal, for the factor VIII is not involved in the function platelet function.

Question 2

What is the clinical bleeding reference range for all deficiency factors?

Answer 2

50-150%

If it is more than 150%, then it would be considered prolonged