Chapter 9 10 11 Flashcards
random change in the DNA due to errors in replication that occur without known cause
Spontaneous mutations
result from exposure to known mutagens, physical (primarily radiation) or chemical agents that interact with DNA in a disruptive manner
Induced mutations
addition, deletion, or substitution of a few bases
Point mutation
causes change in a single amino acid
Missense mutation
changes a normal codon into a stop codon
Nonsense mutation
alters a base but does not change the amino acid
Silent mutation
when a mutated gene reverses to its original base composition
Back-mutation
when the reading frame of the mRNA is altered
Frameshift mutation
Substance that causes mutation
Mutagen
Cancer causing substance
Carcinogen
Substance or chemical that causes mutation in embryos
Tetrogrn
Cancer causing genes
Onco genes
Fredrick Griffith
Change in phenotype with the mouse expirment
Avery mcloud mccarty
Heat killed smooth strain and fractions it to 5 biological factors lipids carbohydrates proteins dna and rna and came to conclude dna is responsible for transformation
Breaking and joining of two dna segments to form a new recombinant that will differ from either parent
Recombination
Plasmid transfer from one bacteria to another bacteria
Conjugation
Recombination of the plasmid and bacteria chromosome results in
HFr
Gene transfer from one bacterium to another facilitated by viral vector virus
Transduction
Viruses that infect bacteria
Bacteriphage
The virus kills the host by lysis upon infection of host cells
Lyric cycle