Chapter 8 -neoplastic diseases of bone Flashcards
1
Q
A developmental disease characterized by the replacement of bone with abnormal fibrous connective tissue with varying amounts of calcified material
A
Fibrous Dysplasia
2
Q
The underlying cause of fibrous dysplasia
A
GNAS gene genetic mutation
3
Q
Polyostotic Fibrous Dysplasia
A
occurs in children younger than 10
female predilection
most cases are asymptomatic
4
Q
Another form of polyostotic fibrous dysplasia
A
Albright syndrome
5
Q
condition with endocrine abnormalities and precocious puberty in females deforming the skeleton
A
Albright syndrome or McCune Albright syndrome
6
Q
Pagets disease is most common in what age?
A
Men over 50
7
Q
When Paget disease of bone is found in the Jaw, which is more affected?
A
Maxilla is more affected than the mandible
8
Q
A
