Chapter 8: Metabolism Flashcards

1
Q
  • all chemical reactions that take place in cells to break down or build molecules
  • Anabolism or catabolism
A

Metabolism

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2
Q
  • a series of linked reactions, each catalyzed by a specific enzyme
  • produce energy and cellular compounds
A

Metabolic Pathway

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3
Q

When we eat foods, it is digested to smaller molecules

A
  • polysaccharides
  • lipids
  • proteins
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4
Q

As the glucose, fatty acids, and amino acids are broken down further, _____ is ______

A

energy is released

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5
Q

What happens to the energy from our foods since we do not use it all at once?

A

we store energy in the cells as high-energy adenosine triphosphate, ATP

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6
Q

ATP is later broken down obtain energy to do work in our bodies:

A
  • contracting muscles
  • synthesizing large molecules
  • sending nerve impulses
  • moving substances across cell membranes
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7
Q

Metabolism involves:

A
  • Catabolic reactions
  • Anabolic reactions
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8
Q

It break down large, complex molecules to provide energy and smaller molecules

A

Catabolic reactions

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9
Q

It uses ATP energy to build larger molecules

A

Anabolic reactions

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10
Q

Stages of Metabolism:
Catabolic reactions

A

Stage 1: Digestion and hydrolysis
Stage 2: Degradation
Stage 3: Oxidation

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11
Q

It break down large molecules to smaller ones that enter the bloodstream

A

Digestion and hydrolysis

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12
Q

It breaks down molecules to two- and three-carbon compounds

A

Degradation

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13
Q

________ of small molecules in the ____ ____ ____ and _______ _______ provide ATP energy

A
  • Oxidation
  • citric acid cycle
  • electron transport
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14
Q

As long as the cells have oxygen, the hydrogen ions and electrons from the ______ _______ are transferred to electron transport to synthesize ATP

A

reduced coenzymes

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14
Q

Adenosine triphosphate (ATP)

A
  • is the energy form stored in cells
  • is obtained from the oxidation of food
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15
Q

It consists of adenine (nitrogen base), a ribose sugar, and three
phosphate groups

A

Adenosine triphosphate (ATP)

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16
Q

Requires ________ to convert ADP + Pito ATP

A

7.3 kcal/mol (or 31 kJ/mol)

17
Q

Hydrolysis of ATP:
The hydrolysis of ATP to ADP releases 7.3 kcal (31 kJ)/mole

A

ATP → ADP + Pi + 7.3 kcal/mol (31 kJ/mol)

18
Q

Hydrolysis of ATP:
The hydrolysis of ADP to AMP releases 7.3 kcal (31 kJ)/mole

A

ADP → AMP + Pi + 7.3 kcal/mol (31 kJ/mol)

19
Q

Phosphate ester bond

A

Low energy bond

20
Q

Phospho anhydride bonds

A

High energy bond

21
Q
  • Used in anabolic reactions
  • The energy-storage molecule
  • Coupled with energy-requiring reactions
A

ATP

22
Q

Hydrolysis products

A

ADP + Pi

23
Q

Oxidation:
Loss of electrons (e-)

A

Reduction:
Gain of electrons (e-)

24
Q

Oxidation:
Loss of hydrogen (H or H+ and e-)

A

Reduction:
Gain of hydrogen (H or H+ and e-)

25
Q

Oxidation:
Gain of oxygen

A

Reduction:
Loss of oxygen

26
Q

Oxidation:
Release of energy

A

Reduction:
Input of energy

27
Q

Participates in reactions that produce a carbonoxygen double bond (C=O)

A

NAD+ (nicotinamide adenine dinucleotide)

27
Q

NAD+ contains

A
  • ADP
  • ribose
  • nicotinamide
28
Q

Reduces to _____ when the nicotinamide group accepts H+ and 2e-

A

NADH

29
Q

Participates in reactions that produce a carbon-carbon double bond (C=C)

A

FAD (flavin adenine dinucleotide)

30
Q

Reduced form of FAD

A

FADH2

31
Q

FAD contains

A
  • ADP
  • riboflavin (vitamin B2)
32
Q

Consists of pantothenic acid (vitamin B5), phosphorylated ADP, and aminoethanethiol

A

Coenzyme A

33
Q

____ ___ ____ such as the two-carbon acetyl group for transfer

A

Activates acyl groups

34
Q

What is the reactive feature of coenzyme A?

A

thiol group (-SH)

35
Q

thiol group (-SH) bonds to a _____ ____ ____ to produce the energy-rich thioester ____ ___

A
  • two-carbon acetyl group
  • acetyl CoA
36
Q

Used to transfer acetyl groups

A

Coenzyme A

37
Q

The coenzyme after C=O bond formation

A

NADH + H+

38
Q
A