Chapter 8: Dental Management Of Pregnant Patients And Lactation Flashcards
Pregnant women fall into which ASA class?
II
Teratogen:
those agents that can induce or increase the incidence of congenital malformations.
Period of ovulation:
1-2 weeks
Alteration in the implantation of the embryo: all or nothing
Period of embryo?
3-8 weeks, phase of rapid differentiation. The main organs are developed, the most important organ malformations occur
Period of fetus?
12-38 weeks, alteration on fetal growth and maturation
Physiological alterations during pregnancy: cardiovascular system
increased cardiac output, heart rate, blood volume, and venous pressure (supine hypotension syndrome), and decreased blood pressure.
Physiological alterations during pregnancy: respiratory system
Mucosal edematization, hoarseness, chest enlargement, and upper costal breathing.
Physiological alterations during pregnancy: renal system
Increased urinary volume
Physiological alterations during pregnancy: digestive system
Change in appetite, nausea, vomiting, constipation, diarrhoea, and heartburn
Physiological alterations during pregnancy: dermatological changes
Chloasma (hypercaptation of melanin)
Physiological alterations during pregnancy: hematological changes
Great need for iron, anemia
Oral changes during pregnancy:
- periodontal alterations
- buccal mucosa alterations
- dental alterations
PBD
Peridontal changes:
- inc estrogen and progesterone
- p intermedia and p gingivalis
- vascular alterations: mucosal erythema, edema, hyperaemia, and tendency to bleed
- gingivitis!!!
Oral mucosa and dental alterations:
Increased estrogen and progesterone
P. Intermedia and P.gingivalis.
Vascular activation—> mucosal erythema, edema, hyperaemia, and tendency to bleed. GINGIVITIS!!!
Alterations of the oral mucosa:
Granuloma of pregnancy (EPULIS GRAVIDATUM)—> vestibular, anterior region, second trimester, <2cm, bleeding and disappears after childbirth or with surgery.
Oral sores.
Dental alterations: increase in caries due to decrease in salivary pH.
Preimplantation stage:
Threshold dose
Possible alterations
Observations
100-200mSv
1-2% embryonic death
Spontaneous abortion rate 10-30%
Organogenesis stage:
Threshold dose
Possible alterations
Observations
500mSv
Skeletal, ocular, gentian abnormalities, and growth retardation
No effect on human below 100-200mSv
Fetal period:
Threshold dose
Possible alterations
Observations
120-200mSv
Mental retardation
Severe mental retardation 500mSv
Late stage (>26 weeks):
Threshold dose
Possible alterations
Observations
100mSv
Increased cancer or leukemia
Natural congenital malformations 2-3%
Wide consensus: doses ___ do not increase the risk of congenital defects in the embryo of the foetus.
100
No RX during the ?
First quarter
There’s currently no international or national legislation that advises?
Taking any action at doses below 100mSv
FDA categories:
• A: controlled studies have shown no risk.
• B: there’s no evidence of risk in the human species.
• C: we cannot rule out the existence of risks.
• D: there’s evidence of risk to the human foetus, but its use is accepted if there’s no vital risk or for serious illness when no safer medication can be prescribed.
• X: contraindicated in pregnancy.
Gold standard of ATB in pregnancy?
Amoxicillin
Crosses placenta and is used in lactancy
Gold standard analgesic in pregnancy:
Paracetamol
Crosses placenta and is used is lactancy