Chapter 79: Pancreatitis and Cholecystitis Flashcards

1
Q
True or False
Most cases (~80%) involve only mild inflammation of the pan- creas, a disease state with a mortality rate of <1%, which generally resolves with only supportive care
A
True
Most cases (~80%) involve only mild inflammation of the pan- creas, a disease state with a mortality rate of <1%, which generally resolves with only supportive care
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2
Q

True or False
About 5% of all patients who undergo endoscopic retrograde cholangio- pancreatography for treatment of gallstones develop pancreatitis within 30 days

A

True
About 5% of all patients who undergo endoscopic retrograde cholangio- pancreatography for treatment of gallstones develop pancreatitis within 30 days

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3
Q

Medications associated with acute pancreatitis can be categorized into three groups

A
  • Antiretrovirals
  • Chemotherapy
  • Immunosuppressants
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4
Q

Can cause potentially fatal pancreatitis

A

2’,3’-Dideoxyinosine

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5
Q

Antiretrovirals that has lower risk of pancreatitis

A
  • Lamivudine

- Nelfinavir

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6
Q

Most common cause of acute pancreatitis

A

Gallstone

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7
Q

True or False

Pain described as lower abdominal pain or dull or colicky pain is highly unlikely to be pancreatitis

A

True

Pain described as lower abdominal pain or dull or colicky pain is highly unlikely to be pancreatitis

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8
Q

Bluish discoloration around the umbilicus signifying hemoperitoneum

A

Cullen’s sign

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9
Q

Reddish-brown discoloration along the flanks signifying retroperitoneal blood or extravasation of pancreatic exudate

A

Grey-Turner sign

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10
Q

True or False

The gold standard laboratory diagnosis for acute pancreatitis is lipase

A

False

There is no gold standard laboratory diagnosis for acute pancreatitis

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11
Q

True or False

Amylase rises within a few hours after the onset of symptoms, peaks within 48 hours, and normalizes in 3 to 5 days

A

True

Amylase rises within a few hours after the onset of symptoms, peaks within 48 hours, and normalizes in 3 to 5 days

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12
Q

This laboratory test predicts gallstone pancreatitis

A

Alanine aminotransferase (ALT) >150U/L

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13
Q

Characteristic findings in IV contrast abdominal CT

A

(1) pancreatic parenchymal inflammation with or without peripancreatic fat inflammation
(2) pancreatic parenchymal necrosis or peripancreatic necrosis
(3) peripancreatic fluid collection
(4) pancreatic pseudocyst

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14
Q

How fluids prevents complications in pancreatitis?

A

The benefit of fluid resuscitation may result from increased micro- and macrocirculatory support of the pancreas, which prevents complications such as pancreatic necrosis

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15
Q

Which fluid will you give in acute pancreatitis?

A

PLR. Because PNSS may cause a nongap hyperchloremic acidosis and can worsen pancreatitis

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16
Q

Complication of acute pancreatitis that is characterized by transient organ failure (<48 hours), local complications, or systemic complications

A

Moderately severe acute pancreatitis

17
Q

When is the best time to do CT scan in acute pancreatitis?

A

At least 72hours after the onset of symptoms

18
Q

True or False
Systemic inflammatory response syndrome at admission and persistent at 48 hours predicts severe acute pancreatitis more simply and as accurately as the various scoring systems

A

True
Systemic inflammatory response syndrome at admission and persistent at 48 hours predicts severe acute pancreatitis more simply and as accurately as the various scoring systems

19
Q

Progression of acute to chronic pancreatitis is common in what population?

20
Q

Most common symptoms of gallstone?

A

Asymptomatic

21
Q

The most common complication of gallstone disease

A

Biliary colic

22
Q

Primary choledocholithiasis

A

Gallstones within the common bile duct arising from within the bile duct

23
Q

Secondary choledocholithiasis

A

Gallstone within the common bile duct that formed in the gallbladder and then migrating to the common bile duct

24
Q

Microlithiasis composed of cholesterol crystals, calcium bilirubinate pigment, and other calcium salts

A

Biliary sludge

25
True or False Acute acalculous cholecystitis is more common than acute calculous cholecystitis and it is less likely to result in complications
False Acute acalculous cholecystitis is less common than acute calculous cholecystitis and it is more likely to result in complications
26
Classification of gallstone?
- Pigment stone (brown and black) | - Cholesterol stone
27
Most common pathogen seen in acute cholecystitis
Polymicrobial infection
28
Most common classification of stone in gallstone?
Cholesterol stone which is radioluscent
29
Classification of stone in gallstone that more common in asian
Brown stone
30
Biliary colic demonstrates significant circadian periodicity, with a peak in symptom occurrence around ____
Biliary colic demonstrates significant circadian periodicity, with a peak in symptom occurrence around midnight
31
Diagnostic criteria for acute cholecystitis
Local signs: Murphy’s sign Right upper quadrant mass, pain, or tenderness Systemic signs: Fever Elevated C-reactive protein Elevated WBC count Suspected: One local sign and one systemic sign Definite: One local sign, one systemic sign, and imaging findings of acute cholecystitis
32
The most sensitive and specific serum marker of choledocholithiasis
Abnormal γ-glutamyl transpeptidase is the most sensitive and specific serum marker of choledocholithiasis
33
The imaging modality of choice for acute cholecystitis
Abdominal US
34
Normal diameter of common bile duct
<5mm
35
First line of therapy in acute cholecystitis inn treating pain
NSAIDS IV
36
The classic radiographic appearance of gallstone ileum?
Rigler's triad: a small bowel obstruction, pneumobilia, and an ectopic gallstone
37
Complications of acalculous cholecystitis
Gangrene and perforation
38
A common cause of postcholecystectomy pain
Choledocholithiasis