Chapter 7 Flashcards
The boundary that separates the living cell from its surroundings
Plasma Membrane
The plasma membrane exhibits __________, allowing some substances to cross it more easily than others
Selective Permeability
Are fluid mosaics of lipids and proteins
Cellular Membranes
The most important lipid in the plasma membrane
Phospholipids
Phospholipids are ________ molecules, containing ________ and ________ regions
Amphipathic; Hydrophobic; Hydrophilic
States that a membrane is a fluid structure with a “mosaic” of various proteins embedded in it
Fluid Mosaic Model
______ have been chemically analyzed and found to be made of _____ and ______
Membranes; Proteins; Lipids
Scientists studying the plasma membrane reasoned that it must be a ________
Phospholipid bilayer
In 1935, _______ and _______ proposed a sandwich model in which the phospholipid bilayer lies between two layers of globular proteins
Hugh Davson; James Danielli
In 1972, _______ proposed that the membrane is a mosaic of proteins dispersed within the bilayer, with only the hydrophilic regions exposed to water
S.J. Singer and G. Nicolson
_______ in the plasma membrane can move within the bilayer
Phospholipids
As temperatures cool, membranes switch from a _____ state to a ______ state
Fluid; Solid
Membranes rich in unsaturated fatty acids are more ______ than those rich in saturated fatty acids
Fluid
Membranes must be _____ to work properly; they are usually about as fluid as salad oil
Fluid
The steroid, _______ has different effects on membrane fluidity at different temperatures
Steroid
At _______ temperatures, cholesterol restrains movement of phospholipids
Warm
At ________ temperatures, it maintains fluidity by preventing tight packaging
Cool
Determine most of the membrane’s specific functions
Proteins
Are bound to the surface of the membrane
Peripheral proteins
Penetrate the hydrophobic core
Integral proteins
Integral proteins that span the membrane are called
Transmembrane proteins
6 major functions of membrane proteins
- Transport
- Enzymatic Activity
- Signal transduction
- Cell-cell recognition
- Intercellular joining
- Attachment to the cytoskeleton and extracellular matrix
Membrane carbohydrates may be covalently bonded to lipids forming
Glycolipids
Membrane carbohydrates may be covalently bonded to proteins forming
Glycoproteins