Chapter 7 + 8

Question 1

What isthe definition of genotyping

Answer 1

Theprocess of determning differences in the genotype of an individual by examinig the individuals DNA sequence and comparing it to another individuals sequenceor reference seuquences

Question 2

What is usually the frequence of a polymorphic trait in the population?

Answer 2

> 1%

Question 3

Term: presence of more than one genetically distinct allele of a DNA or protein sequence ina population

Answer 3

Polymorphism

Question 4

Whatis the difference between a mutation and polymorphism?

Answer 4

• mutation: single event, physical in one individual/cell. Mutations can give rise to polymorphism if it not lethal and the frequency in the population increases.
• polymorphism: a population atrribute.

Question 5

What are the four different polymorphisms?

Answer 5

• SNPs (1bp)
• microsatellite (1 -4 bp)
• minisatellite (9-64 bp)
• CNV: copy number variation, relatively large region of the genome