Chapter 64: Management of Patients with Neurologic Infections, Autoimmune Disorders, and Neuropathies

Question 1

1. A client with possible bacterial meningitis is admitted to the ICU. What assessment
   finding would the nurse expect for a client with this diagnosis?
   A. Pain upon ankle dorsiflexion of the foot
   B. Neck flexion produces flexion of knees and hips
   C. Inability to stand with eyes closed and arms extended without swaying
   D. Numbness and tingling in the lower extremities

Answer 1

ANS: B
Rationale: Clinical manifestations of bacterial meningitis include a positive Brudzinski sign. Neck flexion producing flexion of knees and hips correlates with a positive Brudzinski sign. Positive Homan sign (pain upon dorsiflexion of the foot) and negative Romberg sign (inability to stand with eyes closed and arms extended) are not expected assessment findings for the client with bacterial meningitis. Peripheral neuropathy manifests as numbness and tingling in the lower extremities. Again, this would not be an initial assessment to rule out bacterial meningitis.

Question 2

2. The nurse is planning discharge education for a client with trigeminal neuralgia. The
   nurse knows to include information about factors that precipitate an attack. What would
   the nurse be correct in teaching the client to avoid?
   A. Washing the face
   B. Exposing the skin to sunlight
   C. Using artificial tears
   D. Drinking large amounts of fluids

Answer 2

ANS: A
Rationale: Washing the face should be avoided if possible because this activity can trigger an attack of pain in a client with trigeminal neuralgia. Using artificial tears would be an
appropriate behavior. Exposing the skin to sunlight would not be harmful to this client. Temperature extremes in beverages should be avoided.

Question 3

3. The nurse is caring for a client with multiple sclerosis (MS). The client tells the nurse
   the hardest thing to deal with is the fatigue. When teaching the client how to reduce
   fatigue, what action should the nurse suggest?
   A. Taking a hot bath at least once daily
   B. Resting in an air-conditioned room whenever possible
   C. Increasing the dose of muscle relaxants
   D. Avoiding naps during the day

Answer 3

ANS: B
Rationale: Fatigue is a common symptom of clients with MS. Lowering the body temperature by resting in an air-conditioned room may relieve fatigue; however,
extreme cold should be avoided. A hot bath or shower can increase body temperature, producing fatigue. Muscle relaxants, prescribed to reduce spasticity, can cause
drowsiness and fatigue. Planning for frequent rest periods and naps can relieve fatigue. Other measures to reduce fatigue in the client with MS include treating depression, using occupational therapy to learn energy conservation techniques, and reducing spasticity.

Question 4

4. A client with Guillain-Barré syndrome has experienced a sharp decline in vital capacity.
   What is the nurse’s most appropriate action?
   A. Administer bronchodilators as ordered.
   B. Remind the client of the importance of deep breathing and coughing exercises.
   C. Prepare to assist with intubation.
   D. Administer supplementary oxygen by nasal cannula.

Answer 4

ANS: C
Rationale: For the client with Guillain-Barré syndrome, mechanical ventilation is required if the vital capacity falls, making spontaneous breathing impossible and tissue
oxygenation inadequate. Each of the other listed actions is likely insufficient to meet the client’s oxygenation needs.

Question 5

5. A client diagnosed with Bell palsy is being cared for on an outpatient basis. During
   health education, the nurse should promote which of the following actions?
   A. Applying a protective eye shield at night
   B. Chewing on the affected side to prevent unilateral neglect
   C. Avoiding the use of analgesics whenever possible
   D. Avoiding brushing the teeth

Answer 5

ANS: A
Rationale: Corneal irritation and ulceration may occur if the eye is unprotected. While paralysis lasts, the involved eye must be protected. The client should be encouraged to
eat on the unaffected side due to swallowing difficulties. Analgesics are used to control the facial pain. The client should continue to provide self-care including oral hygiene.

Question 6

6. The nurse is working with a client who is newly diagnosed with MS. What basic
   information should the nurse provide to the client?
   A. MS is a progressive demyelinating disease of the nervous system.
   B. MS usually occurs more frequently in men.
   C. MS typically has an acute onset.
   D. MS is sometimes caused by a bacterial infection.

Answer 6

ANS: A
Rationale: MS is a chronic, degenerative, progressive disease of the central nervous system, characterized by the occurrence of small patches of demyelination in the brain
and spinal cord. The cause of MS is not known, and the disease affects twice as many women as men.

Question 7

7. The nurse is creating a plan of care for a client who has a recent diagnosis of MS. Which
   of the following should the nurse include in the client’s care plan?
   A. Encourage the client to void every hour.
   B. Order a low-residue diet.
   C. Provide total assistance with all ADLs.
   D. Instruct the client on daily muscle stretching.

Answer 7

ANS: D
Rationale: A client diagnosed with MS should be encouraged to increase the fiber in his or her diet and void 30 minutes after drinking to help train the bladder. The client should
participate in daily muscle stretching to help alleviate and relax muscle spasms.

Question 8

8. A client with metastatic cancer has developed trigeminal neuralgia and is taking
   carbamazepine for pain relief. What principle applies to the administration of this
   medication?
   A. Carbamazepine is not known to have serious adverse effects.
   B. The client should be monitored for bone marrow depression.
   C. Side effects of the medication include renal dysfunction.
   D. The medication should be first taken in the maximum dosage form to be
   effective.

Answer 8

ANS: B
Rationale: The anticonvulsant agents carbamazepine and phenytoin relieve pain in most clients diagnosed with trigeminal neuralgia by reducing the transmission of impulses at certain nerve terminals. Side effects include nausea, dizziness, drowsiness, and aplastic anemia. Carbamazepine should be gradually increased until pain relief is obtained.

Question 9

9. A client presents to the clinic reporting a headache. The nurse notes that the client is
   guarding the neck and tells the nurse about stiffness in the neck area. The nurse suspects
   the client may have meningitis. What is another well-recognized sign of this infection?
   A. Negative Brudzinski sign
   B. Positive Kernig sign
   C. Hyperpatellar reflex
   D. Sluggish pupil reaction

Answer 9

ANS: B
Rationale: Meningeal irritation results in a number of well-recognized signs commonly seen in meningitis, such as a positive Kernig sign, a positive Brudzinski sign, and
photophobia. Hyperpatellar reflex and a sluggish pupil reaction are not commonly recognized signs of meningitis.

Question 10

10. The nurse is developing a plan of care for a client newly diagnosed with Bell palsy. The
    nurse’s plan of care should address what characteristic manifestation of this disease?
    A. Tinnitus
    B. Facial paralysis
    C. Pain at the base of the tongue
    D. Diplopia

Answer 10

ANS: B
Rationale: Bell palsy is characterized by facial dysfunction, weakness, and paralysis. It does not result in diplopia, pain at the base of the tongue, or tinnitus.

Question 11

11. The nurse planning caring for a client diagnosed with Guillain-Barré syndrome. The
    nurse’s communication with the client should reflect the possibility of which sign or
    symptom of the disease?
    A. Intermittent hearing loss
    B. Tinnitus
    C. Tongue enlargement
    D. Vocal paralysis

Answer 11

ANS: D
Rationale: Guillain-Barré syndrome is a disorder of the vagus nerve. Clinical manifestations include vocal paralysis, dysphagia, and voice changes (temporary or permanent hoarseness). Hearing deficits, tinnitus, and tongue enlargement are not associated with this disease.

Question 12

12. The nurse is preparing to provide care for a client diagnosed with myasthenia gravis.
    The nurse should know that the signs and symptoms of the disease are the result of what
    issue?
    A. Genetic dysfunction
    B. Upper and lower motor neuron lesions
    C. Decreased conduction of impulses in an upper motor neuron lesion
    D. A lower motor neuron lesion

Answer 12

ANS: D
Rationale: Myasthenia gravis is characterized by a weakness of muscles, especially in the face and throat, caused by a lower neuron lesion at the myoneural junction. It is not a
genetic disorder. A combined upper and lower neuron lesion generally occurs as a result of spinal injuries. A lesion involving cranial nerves and their axons in the spinal cord
would cause decreased conduction of impulses at an upper motor neuron.

Question 13

13. A client with suspected Creutzfeldt-Jakob disease (CJD) is being admitted to the unit.
    The nurse would expect what diagnostic test to be ordered for this client?
    A. Cerebral angiography
    B. ABG analysis
    C. CT
    D. EEG

Answer 13

ANS: D
Rationale: The EEG reveals a characteristic pattern over the duration of CJD. A CT scan may be used to rule out disorders that may mimic the symptoms of CJD. ABGs would not
be necessary until the later stages of CJD; they would not be utilized as a diagnostic test. Cerebral angiography is not used to diagnose CJD.

Question 14

14. To alleviate pain associated with trigeminal neuralgia, a client is taking
    carbamazepine. What health education should the nurse provide to the client before
    initiating this treatment?
    A. Concurrent use of calcium supplements is contraindicated.
    B. Blood levels of the drug must be monitored.
    C. The drug is likely to cause hyperactivity and agitation.
    D. Carbamazepine can cause tinnitus during the first few days of treatment.

Answer 14

ANS: B
Rationale: Side effects of carbamazepine include nausea, dizziness, drowsiness, and aplastic anemia. The client must also be monitored for bone marrow depression during
long-term therapy. Skin discoloration, insomnia, and tinnitus are not side effects of the drug.

Question 15

15. A client with herpes simplex virus encephalitis (HSV) has been admitted to the ICU.
    What medication would the nurse expect the health care provider to order for the
    treatment of this disease process?
    A. Cyclosporine
    B. Acyclovir
    C. Cyclobenzaprine
    D. Ampicillin

Answer 15

ANS: B
Rationale: Antiviral agents, acyclovir and ganciclovir, are the medications of choice in the treatment of HSV. The mode of action is the inhibition of viral DNA replication. To prevent
relapse, treatment would continue for up to 3 weeks. Cyclosporine is an immunosuppressant and antirheumatic. Cyclobenzaprine is a centrally acting skeletal muscle relaxant. Ampicillin, an antibiotic, is ineffective against viruses.

Question 16

16. A middle-aged client has sought care from the primary provider and undergone
    diagnostic testing that has resulted in a diagnosis of MS. What sign or symptom is most
    likely to have prompted the client to seek care?
    A. Cognitive declines
    B. Personality changes
    C. Contractures
    D. Difficulty in coordination

Answer 16

ANS: D
Rationale: The symptoms of MS most commonly reported are fatigue, depression, weakness, numbness, difficulty in coordination, loss of balance, spasticity, and pain. Cognitive changes and contractures usually occur later in the disease.

Question 17

17. A nurse is planning the care of a 28-year-old client hospitalized with a diagnosis of
    myasthenia gravis. What approach would be most appropriate for the care and
    scheduling of diagnostic procedures for this client?
    A. All at one time, to provide a longer rest period
    B. Before meals, to stimulate the client’s appetite
    C. In the morning, with frequent rest periods
    D. Before bedtime, to promote rest

Answer 17

ANS: C
Rationale: Procedures should be spaced to allow for rest in between. Procedures should be avoided before meals, or the client may be too exhausted to eat. Procedures should be avoided near bedtime if possible.

Question 18

18. A 33-year-old client presents at the clinic with reports of weakness, incoordination,
    dizziness, and loss of balance. The client is hospitalized and diagnosed with MS. What
    sign or symptom, revealed during the initial assessment, is typical of MS?
    A. Diplopia, history of increased fatigue, and decreased or absent deep tendon
    reflexes
    B. Flexor spasm, clonus, and negative Babinski reflex
    C. Blurred vision, intention tremor, and urinary hesitancy
    D. Hyperactive abdominal reflexes and history of unsteady gait and episodic
    paresthesia in both legs

Answer 18

ANS: C
Rationale: Optic neuritis, leading to blurred vision, is a common early sign of MS, as is intention tremor (tremor when performing an activity). Nerve damage can cause urinary hesitancy. In MS, deep tendon reflexes are increased or hyperactive. A positive Babinski reflex is found in MS. Abdominal reflexes are absent with MS.

Question 19

19. The nurse is developing a plan of care for a client with Guillain-Barré syndrome.
    Which of the following interventions should the nurse prioritize for this client?
    A. Using the incentive spirometer as prescribed
    B. Maintaining the client on bed rest
    C. Providing aids to compensate for loss of vision
    D. Assessing frequently for loss of cognitive function

Answer 19

ANS: A
Rationale: Respiratory function can be maximized with incentive spirometry and chest physiotherapy. Nursing interventions toward enhancing physical mobility should be
utilized. Nursing interventions are aimed at preventing a deep vein thrombosis. Guillain-Barré syndrome does not affect cognitive function or vision.

Question 20

20. A 69-year-old client is brought to the ED by ambulance because a family member
    found the client lying on the floor disoriented and lethargic. The health care provider
    suspects bacterial meningitis and admits the client to the ICU. What interventions should
    the nurse perform? Select all that apply.
    A. Obtain a blood type and cross-match.
    B. Administer antipyretics as prescribed.
    C. Perform frequent neurologic assessments.
    D. Monitor pain levels and administer analgesics.
    E. Place the client in positive pressure isolation.

Answer 20

ANS: B, C, D
Rationale: Clients with meningitis require antipyretics and analgesia to treat fever and pain. The client’s neurologic status must be monitored closely. Transfusions are not
anticipated. Infection control precautions are implemented, but positive pressure isolation is not necessary because the client is not immunocompromised.

Question 21

21. The critical care nurse is caring for 25-year-old admitted to the ICU with a brain
    abscess. What is a priority nursing responsibility in the care of this client?
    A. Maintaining the client’s functional independence
    B. Providing health education
    C. Monitoring neurologic status closely
    D. Promoting mobility

Answer 21

ANS: C
Rationale: Vigilant neurologic monitoring is a key aspect of caring for a client who has a brain abscess. This supersedes education, ADLs, and mobility, even though these are all
valid and important aspects of nursing care.

Question 22

22. A client is being admitted to the neurologic ICU with suspected herpes simplex virus
    encephalitis. What nursing action best addresses the client’s reported headache?
    A. Initiating a client-controlled analgesia (PCA) of morphine sulfate
    B. Administering hydromorphone IV as needed
    C. Dimming the lights and reducing stimulation
    D. Distracting the client with activity

Answer 22

ANS: C
Rationale: Comfort measures to reduce headache include dimming the lights, limiting noise and visitors, grouping nursing interventions, and administering analgesic agents.
Opioid analgesic medications may mask neurologic symptoms; therefore, they are used cautiously. Nonopioid analgesics may be preferred. Distraction is unlikely to be effective, and may exacerbate the client’s pain.

Question 23

23. A client is admitted through the ED with suspected St. Louis encephalitis. The unique
    clinical feature of St. Louis encephalitis will make what nursing action a priority?
    A. Serial assessments of hemoglobin levels
    B. Blood glucose monitoring
    C. Close monitoring of fluid balance
    D. Assessment of pain along dermatomes

Answer 23

ANS: C
Rationale: A unique clinical feature of St. Louis encephalitis is SIADH with hyponatremia. As such, it is important to monitor the client’s intake and output closely.

Question 24

24. The nurse is caring for a 77-year-old client with MS. The client is very concerned
    about the progress of the disease and what the future holds. The nurse should know that
    older adult clients with MS are known to be particularly concerned about what variables?
    Select all that apply.
    A. Possible nursing home placement
    B. Pain associated with physical therapy
    C. Increasing disability
    D. Becoming a burden on the family
    E. Loss of appetite

Answer 24

ANS: A, C, D
Rationale: Older adult clients with MS are particularly concerned about increasing disability, family burden, marital concern, and the possible future need for nursing home
care. Older adults with MS are not noted to have particular concerns regarding the pain of therapy or loss of appetite.

Question 25

25. The clinic nurse is caring for a client with a recent diagnosis of myasthenia gravis. The
    client has begun treatment with pyridostigmine bromide. What change in status would
    most clearly suggest a therapeutic benefit of this medication?
    A. Increased muscle strength
    B. Decreased pain
    C. Improved GI function
    D. Improved cognition

Answer 25

ANS: A
Rationale: The goal of treatment using pyridostigmine bromide is improvement of muscle strength and control of fatigue. The drug is not intended to treat pain, or cognitive or GI functions.

Question 26

26. The critical care nurse is admitting a client in myasthenic crisis to the ICU. The nurse
    should prioritize what nursing action in the immediate care of this client?
    A. Suctioning secretions
    B. Facilitating ABG analysis
    C. Providing ventilatory assistance
    D. Administering tube feedings

Answer 26

ANS: C
Rationale: Providing ventilatory assistance takes precedence in the immediate management of the client with myasthenic crisis. It may be necessary to suction secretions and/or provide tube feedings, but they are not the priority for this client. ABG analysis will be done, but this is also not the priority.

Question 27

27. The nurse caring for a client in ICU diagnosed with Guillain-Barré syndrome should
    prioritize monitoring for what potential complication?
    A. Impaired skin integrity
    B. Cognitive deficits
    C. Hemorrhage
    D. Autonomic dysfunction

Answer 27

ANS: D
Rationale: Based on the assessment data, potential complications that may develop include respiratory failure and autonomic dysfunction. Skin breakdown, decreased
cognition, and hemorrhage are not complications of Guillain-Barré syndrome.

Question 28

28. The nurse is teaching a client with Guillain-Barré syndrome about the disease. The
    client asks how the client can ever recover if demyelination of the nerves is occurring.
    What would be the nurse’s best response?
    A. “Guillain-Barré spares the Schwann cell, which allows for remyelination in the
    recovery phase of the disease.”
    B. “In Guillain-Barré, Schwann cells replicate themselves before the disease
    destroys them, so remyelination is possible.”
    C. “I know you understand that nerve cells do not remyelinate, so the health care
    provider is the best one to answer your question.”
    D. “For some reason, in Guillain-Barré, Schwann cells become activated and take
    over the remyelination process.”

Answer 28

ANS: A
Rationale: Myelin is a complex substance that covers nerves, providing insulation and speeding the conduction of impulses from the cell body to the dendrites. The cell that
produces myelin in the peripheral nervous system is the Schwann cell. In Guillain-Barré syndrome, the Schwann cell is spared, allowing for remyelination in the recovery phase of the disease. The nurse should avoid downplaying the client’s concerns by wholly deferring to the health care provider.

Question 29

29. A client diagnosed with myasthenia gravis has been hospitalized to receive
    therapeutic plasma exchange (TPE) for a myasthenic exacerbation. The nurse should
    anticipate what therapeutic response?
    A. Permanent improvement after 4 to 6 months of treatment
    B. Symptom improvement that lasts a few weeks after TPE ceases
    C. Permanent improvement after 60 to 90 treatments
    D. Gradual improvement over several months

Answer 29

ANS: B
Rationale: Symptoms improve in 75% of clients undergoing TPE; however, improvement lasts only a few weeks after treatment is completed.

Question 30

30. The nurse is discharging a client home after surgery for trigeminal neuralgia. What
    advice should the nurse provide to this client in order to reduce the risk of injury?
    A. Avoid watching television or using a computer for more than 1 hour at a time.
    B. Use over-the-counter antibiotic eye drops for at least 14 days.
    C. Avoid rubbing the eye on the affected side of the face.
    D. Rinse the eye on the affected side with normal saline daily for 1 week.

Answer 30

ANS: C
Rationale: If the surgery results in sensory deficits to the affected side of the face, the client is instructed not to rub the eye because the pain of a resulting injury will not be
detected. There is no need to limit TV viewing or to rinse the eye daily. Antibiotics may or may not be prescribed, and these would not reduce the risk of injury.

Question 31

31. A client diagnosed with Bell palsy is having decreased sensitivity to touch of the
    involved nerve. What should the nurse recommend to prevent atrophy of the muscles?
    A. Blowing up balloons
    B. Deliberately frowning
    C. Smiling repeatedly
    D. Whistling

Answer 31

ANS: D
Rationale: Facial exercises, such as wrinkling the forehead, blowing out the cheeks, and whistling, may be performed with the aid of a mirror to prevent muscle atrophy. Blowing
up balloons, frowning, and smiling are not considered facial exercises.

Question 32

32. A client with diabetes presents to the clinic and is diagnosed with a mononeuropathy.
    This client’s nursing care should involve which of the following?
    A. Protection of the affected limb from injury
    B. Passive and active ROM exercises for the affected limb
    C. Education about improvements to glycemic control
    D. Interventions to prevent contractures

Answer 32

ANS: A
Rationale: Nursing care involves protection of the affected limb or area from injury, as well as appropriate client teaching about mononeuropathy and its treatment. Nursing
care for this client does not likely involve exercises or assistive devices, since these are unrelated to the etiology of the disease. Improvements to diabetes management may or
may not be necessary.

Question 33

33. A client diagnosed with MS has been admitted to the medical unit for treatment of an
    MS exacerbation. Included in the admission orders is baclofen. What should the nurse
    identify as an expected outcome of this treatment?
    A. Reduction in the appearance of new lesions on the MRI
    B. Decreased muscle spasms in the lower extremities
    C. Increased muscle strength in the upper extremities
    D. Decreased severity and duration of exacerbations

Answer 33

ANS: B
Rationale: Baclofen, a -aminobutyric acid (GABA) agonist, is the medication of choice in treating spasms. It can be given orally or by intrathecal injection. Avonex and Betaseron
reduce the appearance of new lesions on the MRI. Corticosteroids limit the severity and duration of exacerbations. Anticholinesterase agents increase muscle strength in the upper extremities.

Question 34

34. A 73-year-old client comes to the clinic reporting weakness and loss of sensation in
    the feet and legs. Assessment of the client shows decreased reflexes bilaterally. Why
    would it be a challenge to diagnose a peripheral neuropathy in this client?
    A. Older adults are often vague historians.
    B. Older adults have fewer peripheral nerves than younger adults.
    C. Many older adults are hesitant to admit that their body is changing.
    D. Many symptoms can be the result of normal aging process.

Answer 34

ANS: D
Rationale: The diagnosis of peripheral neuropathy in the geriatric population is challenging because many symptoms, such as decreased reflexes, can be associated with the normal aging process. In this scenario, the client has come to the clinic seeking help for this problem; this does not indicate a desire on the part of the client to withhold
information from the health care giver. The normal aging process does not include a diminishing number of peripheral nerves.

Question 35

35. A client with MS has developed dysphagia as a result of cranial nerve dysfunction.
    What nursing action should the nurse consequently perform?
    A. Arrange for the client to receive a low residue diet.
    B. Position the client upright during feeding.
    C. Suction the client following each meal.
    D. Withhold liquids until the client has finished eating.

Answer 35

ANS: B
Rationale: Correct, upright positioning is necessary to prevent aspiration in the client with dysphagia. There is no need for a low-residue diet and suctioning should not be
performed unless there is an apparent need. Liquids do not need to be withheld during meals in order to prevent aspiration.

Question 36

36. A 48-year-old client has been diagnosed with trigeminal neuralgia following recent
    episodes of unilateral face pain. The nurse should recognize what implication of this
    diagnosis?
    A. The client will likely require lifelong treatment with anticholinergic medications.
    B. The client has a disproportionate risk of developing myasthenia gravis later in
    life.
    C. The client needs to be assessed for MS.
    D. The disease is self-limiting and the client will achieve pain relief over time.

Answer 36

ANS: C
Rationale: Clients that develop trigeminal neuralgia before age 50 should be evaluated for the coexistent of MS because trigeminal neuralgia occurs in approximately 5% of
clients with MS. Treatment does not include anticholinergics and the disease is not self-limiting. Trigeminal neuralgia is not associated with an increased risk of myasthenia
gravis.

Question 37

37. A client presents at the clinic with pain and weakness in the hands. On assessment,
    the nurse notes diminished reflexes in the upper extremities bilaterally and bilateral loss
    of sensation. The nurse knows that these findings are indicative of what condition?
    A. Guillain-Barré syndrome
    B. Myasthenia gravis
    C. Trigeminal neuralgia
    D. Peripheral nerve disorder

Answer 37

ANS: D
Rationale: The major symptoms of peripheral nerve disorders are loss of sensation, muscle atrophy, weakness, diminished reflexes, pain, and paresthesia (numbness,
tingling) of the extremities. Trigeminal neuralgia is a condition of the fifth cranial nerve that is characterized by paroxysms of pain in the area innervated by any of the three
branches, but most commonly the second and third branches of the trigeminal nerve. Myasthenia gravis, an autoimmune disorder affecting the myoneural junction, is
characterized by varying degrees of weakness of the voluntary muscles. Guillain-Barré syndrome is an autoimmune attack on the peripheral nerve myelin.