Chapter 6 - Other Flashcards
What are the primary cells of the immune system?
T and B lymphocytes
The thymus is responsible for producing what?
mature T lymphocytes
Lymph nodes are responsible for doing what?
filtering the lymph and trapping antigens; lymphocytes, monocytes, and plasma cells are formed in lymph nodes
What is the pathophysiology of AIDS?
reduction of CD4+ helper T cells, resulting in CD4+ T lymphocytopenia
What are the stages of HIV?
- Stage 1: flu-like illness within 2-4 weeks after infection
- Stage 2: clinical latency; asymptomatic HIV infection or chronic HIV infection; can last a decade or longer
- Stage 3: AIDS; HIV destroys so many cells over time that the body can’t fight off infections and disease, resulting in opportunistic illnesses
How is HIV diagnosed?
- CD4 cell count: 500-1200 cells/mm
- testing with HIV-1/HIV-2 antigen/antibody combination immunoassays
- medical evaluation and laboratory evaluation including plasma HIV viral load, blood cell and CD4 count, antiretroviral resistance assay, drug-resistance testing, and testing for STDs
How is AIDS diagnosed?
- CD4 cell count drops below 200 cells/mm or if they develop certain opportunistic illnesses. People with AIDS have a high viral load and are very infectious.
- AIDS-related complex: the presence of acute symptoms secondary to immune system deficiency.
What are red flags associated with AIDS-related treatment?
rash, nausea, nausea and vomiting, diarrhea, headaches, dizziness, fatigue, and pain
How is Chronic Fatigue Syndrome diagnosed?
- The patient must have both of the major criteria and four or more of the eight symptom criteria:
Major criteria: 1) new onset of persistent or relapsing fatigue; must be present for at least eight months; does not resolve with bed rest and reduces daily activity by at least 50%; 2) exclusion of other chronic conditions
Symptom criteria:
- profound or prolonged fatigue; post-exertional malaise lasting more than 24 hours
- a sore throat that is frequent or reoccurring
- tender lymph nodes
- muscle pain (myalgia)
- sleep that is not refreshing
- headache of a new type, pattern or severity
- multijoint pain (arthralgias) without swelling or redness
- significant impairments of short-term memory or concentration
What are the general characteristics of Fibromyalgia Syndrome?
- myalgia
- generalized aching, persistent fatigue (mental and physical)
- sleep disturbances with generalized morning stiffness
- multiple tender points
- additional problems include visual disturbances, spasm, cold intolerance, headaches, irritable bowel or bladder, cognitive problems, restless legs, atypical patterns of numbness and tingling (sensitivity amplification)
What are the criteria for diagnosis Fibromyalgia Syndrome?
two criteria: widespread pain lasting at least 3 months and the presence of 11 positive tender points out a total of 18 (Copenhagen Fibromyalgia Syndrome definition).
What are the three groups of streptococcal infections?
Group A streptococcus (S. pyogenes): pharyngitis, rheumatic fever, scarlet fever, impetigo, necrotizing fasciitis (gangrene), cellulitis, myositis
Group B streptococcus (S. agalactiae): neonatal and adult streptococcal B infections
Group C streptococcus (S. pneumoniae): pneumonia, otitis media, meningitis, endocarditis
T/F: Manual therapy should be used with caution in patients with hematologic disorders
True; as should some modalities (i.e. mechanical compression)
What are some of the causes of anemia?
a decrease in RBC production: nutritional deficiency (iron, vitamin B, folic acid); cellular maturation defects, decreased bone marrow stimulation (hypothyroidism), bone marrow failure (leukemia, aplasia, neoplasm), and genetic defect
Cancer Staging
Stage 0: carcinoma in situ
Stage 1: the tumor is localized, equal to or less than 2 cm; has not spread to lymph nodes
Stage 2: the tumor is locally advanced; 2 cm to 5 cm with or without lymph node involvement
Stage 3: the tumor is locally more advanced; spread to lymph nodes; cancer is designated stage 2 or 3 depending upon the specific type of cancer
Stage 4: the tumor has metastasized, or spread to other organs throughout the body