Chapter 6: Integumentary System Flashcards

1
Q

Dermatology

A

Scientific Study and medical treatment of the integumentary system

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2
Q

Integumentary system

A

The body’s outer layer. Made up skin, hair and nails. Skin is most vulnerable organ.

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3
Q

Epidermis

A

the superficial region that is ABOVE. avascular

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4
Q

Dermis

A

underlies epidermis, most fibrous connective tissue, vascular

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5
Q

Hypodermis

A

Superficial fasica that is mostly adipose tissue.
NOT part of skin.

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6
Q

Thick skin

A

covers front of hands and bottom of feet (palm and souls) (0.5mm) FIVE STRATA

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7
Q

Thin Skin

A

covers rest of the body (0.1mm) has hair follicles, sebaceous glands and oil glands FOUR STRATA

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8
Q

functions of our skin

A

protection, body temperature regulation, cutaneous sensation, metabolic functions, blood reservior, excretion of wastes

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9
Q

Three barriers that are protected

A

Chemical barrier, Physical barrier, Biological barrier

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10
Q

Chemical Barrier

A

-Skin secretes many chemicals

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11
Q

Defensins

A

sebum and defensins fills bacteria. chemical barrier secretes antimicrobial defensin

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12
Q

Melanin

A

provides chemical barrier against UV radiation

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13
Q

Physical Barrier

A

Flat dead kertinizied cells of stratum corneum, surrounded by glycolipids that block most water and water soluble substances

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14
Q

Biological Barriers

A

-epidermis contains phagocytic dendritic cells
-DNA can absorb harmful UV radiation, converting it to harmless heat
-dermis contains macrophages

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15
Q

dendritic cells

A

special type of immune cells that are found in tissues such as skin (boosts immune responses)

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16
Q

thermoregulation

A

the maintenance of the physiologic core body temperature by balancing heat generation with heat loss

17
Q

insensible perspiration

A

under average resting body temperature sweat glands produce 500 ml/ day of UNNOTICEABLE sweat

18
Q

Sensible perspiration

A

Body temperature rises and causes dilation of dermal vessels to increase sweat gland activity (NOTICEABLE sweat)

19
Q

Body in cold temp.

A

dermal vessels constrict cause skin temp to drop

20
Q

Cutaneous sensory receptors

A

-part of the nervous system
-respond to stimuli outside the body, such as temp, touch, and pain

21
Q

Metabolic functions

A

-synthesize vitamin D needed for calcium absorption
-keratinocytes can activate some hormones

22
Q

Cells of epidermis

A

Keratinocytes
Melanocytes
Dendritic cells
Tactile cells

23
Q

Keratinocytes

A

(most abundant)
-Produce fibrous keratin (protien that gives skin its protective properties)
-tightly connected by desmosomes
- most common cells of the epidermis

24
Q

Melanocytes

A

-produce pigment melanin
- protects nucleus from UV damage

25
Q

Dendritic cells

A

are key activators immune cells

26
Q

Tactile cells

A

sensory receptors that sense touch

27
Q

Stratum basale

A

(deepest epidermal layer)
- single layer of stem cells and keratinocytes (stem cells divide and give rise to keratinocytes that migrate to the skin surface to replace lost cells)
-contains a few melanocytes and tactile cells

28
Q

Stratum spinosum

A
  • several layers of keratinocytes joined together by desmosomes and tight junctions
  • contains some dendritic cells
29
Q

Stratum granulosum

A

-three to five layers of flat keratinocytes
- contains dark-staining keratohyalin granules that will slow water loss
-cells above this layer die

30
Q
A