Chapter 6 Glaucoma In Children And Adolescents

Question 1

Triad of PCG

Answer 1

Epiphora, photophobia, and blepharospasm

Question 2

Factors associated with worse prognosis in PCG

Answer 2

Newborn PCG (>50% progress to legal blindness) 
Diagnosis after 1 year of age, cornea > 14mm diameter.

Question 3

PCG demographics

Answer 3

70% bilateral, 65% male, consanguinity greatly increases risk

Question 4

Haab striae

Answer 4

Breaks in December membrane as a result of elevated iop.

Question 5

Until what age does elevated iop cause corneal stretching and buphthalmos?

Answer 5

3

Question 6

JOAG presentation and inheritance

Answer 6

AD- linked to mutations in TIGR/MYOC
Presents between 4 and 35 with elevated iop but usually no corneal enlargement/ haab stria.
Can have progressive myopia until age 10.
May require trabeculectomy or tube shunt.

Question 7

Axenfeld Rieger Syndrome

Answer 7

Anomalous development of neural crest derived anterior segment structures.
Autosomal dominant
Posterior embryotoxon of the corneaand iris adhesions to schwalbe line.
Iris may be normal or have correctopia , hole formation and ectropion uveae