Chapter 6 Antibacterial Drugs: Sulfanomides Flashcards
Drugs that destroy bacteria are?
Bactericidal
Drugs that slow or retard multiplication of bacteria?
Bacteriostatic
How should topical sulfonamides be applied?
Very thin layer over area
Complicated condition from sulfonamide therapy?
Crystallluria
What reaction comes from sulfazalazine?
Skin and urine color change
Two topical sulfonamides used for burns?
Mafenide and Silver Sulfadiazine (causes burning during applications)
What is SMZ-TMP used for?
UTI (take on empty stomach)
What is a reaction of Sulfasalazine therapy?
SJS (red wheels on face and neck)
What is complication of Sulfonamide therapy?
Thrombocytopenia
What is adverse effect to sulfamethoxazole trimethoprim?
Renal failure
What is adverse effect to sulfisoxazole?
Skin rash
Possible effect to diabetics using sulfazalazine?
Hypoglycemia
Best way to determine a drug to treat an infection is?
Culture and sensitivity
What are sulfonamides classified as?
Bacteriostatic ( because they only inhibit the folic acid in bacterial cell)
What are conditions sulfonamides are used for?
UTI, OTTIS MEDIA,ULCERATIVE COLITIS,BACTERIAL INFECTIONS
The 3 most common adverse reactions to Sulfonamide Therapy?
Leukopenia-decrease #wbc
Thrombocytopenia-decrease #platelets
Aplastic Aneemia-deficit rbc production in bone marrow
Comply used for relief of &preventing UTI?
Cranberries and cranberry juice
Who should be cautious in taking sulfonamides?
Older aged people(increase danger for renal impairment)
What therapy causes sensitivity to light?
Sulfonamide therapy
