Chapter 6: Agents and Hazards Flashcards
Hazard
any condition or changing set of circumstances that has the potential to cause an injury (or illness)
Agents
any substances to which a human may be exposed at work or at home
o Physical
o Chemical
o Biological
Biohazards
hazards created by exposure to infectious microorganisms, proteins, or nucleic agents
Chain of infection
the process and conditions by which biological agents are spread from one host to another
Reservoir
the home or environment where the biological agent grows and multiplies
Portal of exit
the path by which a biohazardous agent leaves its host
Mode of transmission
the means or channel by which an agent is carried from one host to another
Portal of entry
the path by which a biohazardous agent gains access to a new host
Susceptible Host
an individual or animal that becomes infected with a biohazardous agent
Chemical Agents
hazards created by exposure to chemicals
Toxicity
o Ability to cause injury to human biological tissue
o Potential degree of seriousness of the hazard of exposure
o Toxicology is the scientific study of poisons
Aerosols
airborne respirable contaminants, such as liquid droplets or solid particulate, dispersed in air, that are of a fine enough particle size to remain suspended for a time
Routes of Entry for Chemicals Include: (4)
o Respiration (inhaling)
o Skin absorption
o Ingestion
o Skin penetration (puncture wounds)
Respiration
o Most human exposure to chemicals due to breathing airborne contaminants
o Five levels of defense:
Nose
Interior of the nasal passage where turbinates are found (spiral or spongy sections of the respiratory system that have a centrifugal effect to help remove aerosols)
Tiny hairs or cilia and mucus
Aerodynamic characteristics of the human lung
Alveoli in lungs (tiny air sacs that dispose of any impurities via the lymph system)
Skin Absorption
o The ability of a chemical to pass easily through the skin is often closely associated with its level of toxicity
o Chemicals that are not rapidly absorbed may produce a localized irritation (dermatitis) which may cause the skin to become white and dry
Ingestion
o Many solvents enter through the mouth and digestive system
Penetration
o When the skin is cut or punctured by any sharp object
Object may be contaminated with a hazardous chemical
o Particular risk for health care workers
Inorganic Solvents
- Acids (1)
2. Bases (14)
Biological Agents
- Natural organisms that can be a risk to humans
- Well known diseases resulting from biological agents are:
o Legionnaires’ disease
o AIDS
o SARS
SARS
- Severe acute respiratory syndrome
- Viral infection (SARS coronavirus)
- Morality rate about 10% according to WHO
- Symptoms
o Flu like (fever, lethargy, cough, sore throat, gastrointestinal problems)
o Appears 2 – 10 days post exposure - Treatment
o Antibiotics are ineffective
o Antipyretics, oxygen, and ventilation work better
Engineering controls for hazard control measures
best is elimination, areas should be properly enclosed, built-in protective systems, ventilation systems, construction seals, sharp disposal containers for needles, or automated equipment like toilets and sinks
Work practices and procedures for hazard control measures
good housekeeping (surfaces are clean, etc.), spills must be cleaned up properly, preventive maintenance such as air filters on exhaust, and thorough recordkeeping (records be kept of employee exposure, workplace air monitoring, and equipment breakdowns and repairs
Administrative control for hazard control measures
training in safe operating and emergency procedures
Personal protective equipment (PPE) for hazard control measures
respiratory protection, each device must be matched to the chemical and biological exposure