Chapter 54 Flashcards
What type of screening test can be done in the 1st trimester ?
plasma protein A and free beta-human chorionic gonadotropin.
The laboratory values of PAPP-A and free beta-hCG can determine ?
chromosomal abnormality, congenital heart defect, skeletal dysplasia, or other syndromes.
what are some additional tests, a parent can choose aside from PAPP-A and free beta-hCG ?
- noninvasive prenatal testing (NIPT)
2. invasive testing such as: chorionic villus sampling (CVS) or amniocentesis
NIPT test can be done as early as?
10 weeks
Which test has a much higher detection, screening test, for down syndrome and trisomy 18/13 ?
NIPT
What four serum markers are done under the maternal serum quad screen?
- alpha-fetoprotein (AFP),
- human chorionic gonadotropin (hCG)
- unconjugated estriol (uE3),
- inhibin-A.
Define: detaild fetal anatomic survey
a detailed evaluation of specified fetal anatomy and biometry that can be seen at the time of examination.
Most ultrasound departments prefer to perform the detailed fetal anatomic survey examination between____ weeks.
18 to 20 weeks
define: Advance maternal age (AMA)
describes a patient who will be 35 or older at the time of delivery
AMA can be an indicator for what?
high-risk pregnancy, example down syndrome
define: hydrops fetalis
a condition in which excessive fluid accumulates within the fetal body cavities.
what are the 2 type of fetal hyprops?
immune hydrops
nonimmune hydrops
immune hydrops is initiated by the_____?
Presence of maternal serum IgG antibody against one of the fetal red blood cell antigens (mixing of blood)
The mixing of maternal and fetal blood, can be prevented? true or false ?
True, with RhoGAM
If a sensitized pregnancy is not treated with RhoGAM, what will happen to fetus ?
Hemolysis: attaches to the fetal RBCs and destroys them.
anema, heart failure, hydrops
Of the ultrasound tools,what is one way to predict fetal anemia?
doppler evaluation of the middle cerebral artery.
define: cordocentesis
a procedure in which a needle is placed into the fetal umbilical vein to obtain a blood sample.
there are two types of fetal blood transfusion, One is cordocentesis and the other______?
intraperitoneal transfusion: ultrasound guidance to place a needle in the peritoneal cavity of the fetus
define Alloimmune thrombocytopenia.
a mother may develop an immune response to fetal platelets.
The result of an Alloimmune thrombocytopenia, the fetus may__?
have a low platelet count and intracerebral hemorrhage
nonimmune hydrops is?
A group of conditions, which hydrops is present in the fetus but is not a result of fetomaternal blood group incompatibility.
what are the most frequent causes for Nonimmune hydrops?
cardiovascular lesions
vaginal bleeding in the 2nd or 3rd trimester can be associated with___?
placental abruption and placenta previa
the condition that the placenta covers the internal os and prohibits the delivery of the fetus, is due to ___?
placenta previa
If the placenta and the internal os distance is less than 2 cm, the condition may be classified as
low-lying placenta